The phytochemical investigation of both volatile and fixed metabolites of Clinopodium taxifolium (Kunth) Govaerts (Lamiaceae) was performed for the first time. It allowed the isolation and characterization of the essential oil and six known compounds: carvacrol (1), squalane (2), uvaol (3), erythrodiol (4), ursolic acid (5), and salvigenin (6). Their structures were identified and characterized...

Thymus daenensis subsp. daenensis is an endemic aromatic and medicinal plant of Iran. The study was conducted to determine variations of antibacterial activity, thymol and carvacrol content in different populations of Thymus daenensis. The flowering aerial parts of Thymus daenensis were collected from ten locations in two provinces, Iran. The antibacterial activity of the extract was tested ass...

As part of an ongoing research program to identify active mosquito repellents, Monarda bradburiana Beck and Monarda fistulosa L. essential oils showed good repellent activity with minimum effective dosages (MED) of 0.055 ± 0.036 and 0.078 ± 0.027 mg/cm(2), respectively, compared to reference standard N,N-diethyl-3-methylbenzamide (DEET) (0.039 ± 0.014 mg/cm(2)). Systematic bioassay-guided fract...

BACKGROUND AND OBJECTIVE: Candida albicans infection is a problem of growing clinical importance, particularly in immunocompromised populations. This study aimed to investigate the inhibitory effect of carvacrol on the hyphae formation and expression of C. albicans HWP1. METHODS: This cross-sectional study was done over a 6-month period in 2016-2017. Vaginal, mouth and  skin surface swabs were...

The insecticidal toxicities of five essential oils against Pochazia shantungensis adults and nymphs, newly recorded pests, were evaluated. The LC50 values of Thymus vulgaris, Ruta graveolens, Citrus aurantium, Leptospermum petersonii and Achillea millefolium oils were recorded as 57.48, 84.44, 92.58, 113.26 and 125.78 mg/L, respectively, against P. shantungensis nymphs using the leaf dipping bi...

We developed wine formulations containing plant essential oils and oil compounds effective against foodborne pathogenic bacteria Escherichia coli O157:H7 and Salmonella enterica. HPLC was used to determine maximum solubility of antimicrobials in wines as well as amounts of antimicrobials extracted by wines from commercial oregano and thyme leaves. Activity of essential oils (cinnamon, lemongras...

Thymol and carvacrol are phenolic isomers with the potential developmental toxicity endocrine disruptions (ED) at low concentrations. However, few reports estimated their ED below 10−6 M (150 μg/L) (MW of thymol carvacrol: 150 g/mol). In this study, both chemicals were determined for 500 μg/kg 50 using chicken embryonic assay, estrogenic activity (EA) 10−12 to 10−7 (1.5 × 10−4 15 by MCF-7 cell ...