Background: Hypothyroidism is associated with dysfunction of the bone turnover with reduced osteoblastic bone formation and osteoclastic bone resorption. Mesenchymal stem cells (MSCs) secrete various factors and cytokines that may stimulate bone regeneration.  The aim of this study was to determine the effects of MSCs-conditioned medium (CM) in hypothyroidism male rats after inducing bone ...

Objective(s): Alcohol consumption induces oxidative stress on bone, which in turn increases the risk of osteoporosis. This study determined the effects of vitamin E on bone strength and bone mineral content in alcohol-induced osteoporotic rats. Materials and Methods: Three months old Sprague Dawley male rats were randomly divided into 5 groups: (I) control group; (II) alcohol (3 g/kg) + normal ...

background: it has been stated that the bone allografts from different tissue banks may lead to various amount of bone induction, so the aim of this study was to evaluate bone regeneration of three demineralized allografts both histologically and histomorphometrically in rabbits calvaria bone defects. materials and methods: in this double-blind randomized experimental animal study, 32 critical ...

introduction: almost all malignant tumors have the potential to eventually produce bone metastasis. the aim of the current study was to report the distribution pattern and imaging characteristics of bone metastases detected by conventional whole body bone scintigraphy in patients with different types of malignancies and to assess their relationship with the complaint of bone pain. methods: as ...

Bone has a capability to repair itself when it is fractured. Repair involves the generation of intermediatetissues, such as fibrous connective tissue, cartilage and woven bone, before final bone healing can occur. Theprocess of cartilage-to-bone transition (CBT) is a key for the achievement of rigid bone healing duringfracture repair. We tested this potential for elastic cartilage using a long ...

Bone drilling process is one the most common processes in orthopedic surgeries and bone breakages treatment. It is also very frequent in dentistry and bone sampling operations. Bone is a complex material and the machining process itself is sensitive so bone drilling is one of the most important, common and sensitive processes in Biomedical Engineering field. Orthopedic surgeries can be improved...

Objective- Bone regeneration is a multifactorial phenomenon which contributed to several factors. It is reported that risedronate is effective for musculoskeletal diseases. The current study was to determine effectiveness of the risedronate-loaded nano capsules for calvaria healing in rabbit.Design- Experimental study.Procedures- 15 white adult male New Zealand rabbits were used. Fo...

bone has a capability to repair itself when it is fractured. repair involves the generation of intermediatetissues, such as fibrous connective tissue, cartilage and woven bone, before final bone healing can occur. theprocess of cartilage-to-bone transition (cbt) is a key for the achievement of rigid bone healing duringfracture repair. we tested this potential for elastic cartilage using a long ...