نتایج جستجو برای: childhood acute myeloid leukemia
تعداد نتایج: 833756 فیلتر نتایج به سال:
Leukemias are the most common malignancies of childhood. Acute lymphoblastic leukemia accounts for 77% of the cases. Eosinophilia is a rare finding in acute lymphoblastic leukemia. A five-years old boy was admitted to rule out appendicitis in surgical ward. There was leukocytosis with sever eosinophilia in complete blood count. Diagnosis of acute lymphoblastic leukemia was made after one month...
Background: Decitabine (5-aza-2'-deoxycytidine, DAC) is a deoxycytidine analog currently used as an effective drug against myelodysplastic syndromes and acute myeloid leukemia. Although various studies have pointed out the epigenetic effects of this drug, its epigenetic mechanisms in different leukemic cell lines are not specified. In this lab trial study, possible epigenetic effects of decitab...
Background: Arsenic trioxide is a chemical compound that has been used as treatment for various diseases. Despite being potentially toxic, this therapy to treat Acute Myeloid Leukemia and investigated possible different types of cancer. Objectives: The present review aims describe the use studies reported in literature Trioxide therapeutic agent Leukemia, Promyelocytic Chronic Multiple Myeloma,...
Background and purpose: Üsing immunotyping in classifying leukemia is growing increasingly. This method provides useful information about proper classifying of leukemia, the prognosis and treatment of this disease. This study is conducted to determine frequency percentage of ÇD markers in patients suffering from acute leukemia who had referred to Ïmam Khomeini Hospital in Ürmia for one year. ...
background : leukemia is the most common cancer in children, accounting for near to half of all childhood cancers. different risk factors might be effective in the occurrence of this cancer such as parental characteristics. this study was done in west azarbaijan province in order to determine the relation between parental characteristics and acute leukemia in children. methods : this matched ca...
3104. 60. Larson RA, Dodge RK, Burns CP, et al. A five-drug remission induction regimen with intensiveconsolidation for adults with acute lymphoblasticleukemia: cancer and leukemia group B study8811. Blood. 1995;85(8):2025-2037. 61. van Schie RM, Brüggemann RJ, HoogerbruggePM, te Loo DM. Effect of azole antifungal therapyon vincristine toxicity in childhood acutelymp...
Acute myeloid leukemia with mutated NPM1 gene and aberrant cytoplasmic expression of nucleophosmin (NPMc(+) acute myeloid leukemia) shows distinctive biological and clinical features. Experimental evidence of the oncogenic potential of the nucleophosmin mutant is, however, still lacking, and it is unclear whether other genetic lesion(s), e.g. FLT3 internal tandem duplication, cooperate with NPM...
Acute myeloid leukemia with mutated NPM1 gene and aberrant cytoplasmic expression of nucleophosmin (NPMc acute myeloid leukemia) shows distinctive biological and clinical features. Experimental evidence of the oncogenic potential of the nucleophosmin mutant is, however, still lacking, and it is unclear whether other genetic lesion(s), e.g. FLT3 internal tandem duplication, cooperate with NPM1 m...
The growth of malignant cells is not only driven by cell-intrinsic factors, but also by the surrounding stroma. Monocytes/Macrophages play an important role in the onset and progression of solid cancers. However, little is known about their role in the development of acute myeloid leukemia, a malignant disease characterized by an aberrant development of the myeloid compartment of the hematopoie...
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