We aimed to systematically investigate the potential association of matrix metalloproteinase (MMP)-9, -3, -2, and -8 gene polymorphisms with susceptibility to periodontitis using meta-analysis. A literature search in PubMed, Embase, and Web of Science was conducted to obtain relevant publications. Finally a total of 16 articles with 24 case-control studies (nine on MMP-9-1562 C/T, seven on MMP-...

Periodontitis is a prevalent oral chronic inflammatory disease which, in severe forms, may exert a major impact on systemic health. Clinical and histological observations, as well as experimental animal studies, suggest involvement of the complement system in periodontitis. However, the precise roles of the various complement components and pathways in periodontitis have only recently started t...

Periodontal diseases are one of the most common complex infections in humans and many other mammals. Infectious agents causing periodontitis are primarily periodontopathogenic bacteria, but disease pathogenesis and progression are immune-mediated. Local inflammation is well characterized, and experimental animal models of periodontitis have also provided mostly consistent data on systemic infla...

Gene polymorphisms and related cell markers in periodontitis lesions Mauro Donati Inflammatory and immune reactions to microbial plaque are the predominant features of periodontitis. Epidemiological studies revealed that differences in periodontitis among individuals could not be explained by differences in oral hygiene alone and that not everybody is equally susceptible. Periodontitis is consi...

background: considering the role of t cells in the pathogenesis of periodontitis, the purpose of this study was to compare the amount of ifnγ, il4 and il17 in advanced periodontal lesions with healthy gum areas to determine each th1, th2 and th17 cells activity in comparison with each other and finally, to compare the value and the role of humoral, cell mediate and autoimmune responses.     met...

BACKGROUND In recent years, evidence has come forth supporting the notion that localized infectious diseases such as periodontal disease may indeed influence a number of systemic diseases. Erectile dysfunction (ED) and chronic periodontitis have common risk factors such as diabetes mellitus, cardiac diseases and smoking etc. AIM The aim was to evaluate the periodontal status of the subjects s...

Introduction : Periodontitis and dental caries may be synergistically associated, negatively associated, or completely independent.The aim of this study was to evaluate the correlation between these two diseases and investigate the prevalence of dental caries in periodontitis. Methods: This cross- sectional study has been performed in 180 samples in two groups: periodontal and control group ...

OBJECTIVE To compare the levels of glutathione (GSH), both oxidized and reduced forms in patients with and without chronic periodontitis in gingival crevicular fluid (GCF). MATERIALS AND METHODS Twenty GCF samples from maxillary quadrants were collected using capillary micropipettes from the chronic periodontitis patients (test group) at baseline before treatment, at 1-month, 3 months, and 6 ...

Objectives: Chronic periodontitis is the most common form of periodontal disease, greatly affecting aesthetics, function as well quality life patients. This study aims to evaluate clinical features and factor associated with chronic periodontitis. Materials methods: was conducted on 60 patients periodontitis, who visited at Family Medical Center, Hue University Medicine Pharmacy, from April 201...