Background: MUTYH DNA glycosylase germline mutations are linked to the recessive inheritance of multiple adenoma. Studies have revealed that germline mutations in this gene are ethnicity related. This study aimed to identify the germline mutations in MUTYH gene and determine their prevalence among Jordanian patients with colorectal adenoma. Methods: In this study, 150 colorectal adenoma patient...

colorectal cancer (crc) is the second leading cause of cancer death. progress has been made in the development of chemotherapy for advanced crc. targeted therapies against vegf or egfr are now commonly used. however, many cases show that tolerance develops to such treatments; therefore, new strategies are required to replace or complement current therapies. nuclear factor-?b (nf-?b) transcripti...

background colorectal cancer (crc) is one of the most common cancers worldwide which is not extensively researched in iran. objectives the present study aims to investigate the epidemiologic characteristics of crc in patients referred to selected hospitals of tehran university of medical sciences. patients and methods in this descriptive-analytic study 218 patients with colorectal cancer were i...

Background: The primary purpose of this literature review is to investigate different views of elective surgery management during the COVID-19 pandemic. In other words, the guidelines about diseases prevention and their proper management during performing elective surgeries have been reviewed. Materials and Methods: Current articles related to COVID-19 and practicing elective surgeries in diff...

Hospitals aim to deliver the highest quality of care. One key priority is to schedule emergency surgeries as quickly as possible, because postponing them generally increases a patient’s risk of complications and even death. In this paper, we consider the case that emergency surgeries are scheduled in one of the elective Operating Rooms (ORs). In this situation, emergency patients are operated o...

synchronous cancer is referred to two or more histological distinct malignancies diagnosed during the same hospital admission. globally more than 1 million people get colorectal cancer yearly resulting in about 0.5 million deaths. vulvar cancer is the fourth most common gynecologic cancer (following the corpus uterine cancer, cancer of ovary and cervix) and comprises only 4 percent of malignanc...

in recent decades, there has been a dramatic increase in the incidence of colorectal cancer in iran, especially in patients less than 50 years old. a national colorectal cancer screening program is the best solution for identifying patients in high risk populations. the research center of gastroenterology and liver disease of shahid beheshti university, m.c., in collaboration, with the ministry...

Operating room (OR) utilization is a key metric of productivity for surgeons and surgical services. It defined as total hours elective surgery performed within OR block time, including turnover divided by the allocated time. To maximize this metric, hospitals have release times built in, which often trigger 72 prior to start day. Vascular among several disciplines that carry high number urgent ...