conclusion distinct neurochemical and histological structure changes (cortico-striatal-thalamic-cortical cycle) exist in patients with first-episode ocd. 1h-mrs is capable of identifying these changes by assessing metabolic abnormalities. objectives this study aims to use magnetic resonance spectroscopy (mrs) to discover substance-metabolism abnormalities of brain circuits in patients with firs...

most obsessive-compulsive disorder (ocd) patients meet psychiatrists 5 to 10 years after onset of ocd .its relatively high prevalence ratio and the delay in seeking help suggest that patients with ocd may seek help at non-psychiatric clinics. the present study was undertaken to provide some epidemiological data on the prevalence and severity of ocd in dermatological patients. the participants i...

the present study aimed to examine the efficacy of metacognitive therapy in treatment of patients with pure obsession.six patients suffering from pure obsession were selected using purposeful sampling method and were included after meeting the inclusion criteria of the study. patients were assessed using the structured clinical interview for dsm- iv axis i disorder - patient edition (scid- i/p)...

background chronic kidney disease (ckd) is a common medical condition among children and obsessive-compulsive disorder (ocd) is a frequent, chronic, costly, and disabling disorder among them. objectives the aim of this study was to investigate obsessive-compulsive disorder (ocd) in children with early stages of ckd, and to compare it with the occurrence of ocd in healthy children. patients and ...

Obsessive-compulsive and sleep disorders are among the most common disorders in general population and therefore aim of present study was to determine role of personality traits in predicting obsessive-compulsive disorder and sleep quality among dormitory students. The participants included 277 university students that were selected randomly. Goldberg big five personality inventory-short form, ...

Intrusive thoughts and compulsive urges to perform stereotyped behaviours are typical symptoms of obsessive-compulsive disorder. Emerging evidence suggests a cognitive bias towards habit formation at the expense of goal-directed performance in obsessive-compulsive disorder. In this study, we test this hypothesis using a novel individualized ecologically valid symptom provocation design: a live ...

Due to the problems of measurement and the lack of nationally representative data, the extent of compulsive buying behaviour (CBB) is relatively unknown. The validity of three different instruments was tested: Edwards Compulsive Buying Scale (ECBS; Edwards, E.A., 1993. Development of a new scale for measuring compulsive buying behaviour. Financial Counseling and Planning. 4, 67-85), Questionnai...

Different lines of evidence point to dysfunction of basal ganglia-thalamocortical circuits in obsessive-compulsive disorder (OCD). It has been hypothesized that the circuits' dysfunction in OCD may be characterized by a relative under-activity of the indirect compared with the direct pathway within these circuits. The present study tested whether lesions of the subthalamic nucleus (STN), a majo...