background: considering the prevalence of leishmaniasis in iran and many side effects associated with pentavalent antimony compounds use in its treatment, this study was designed to evaluate the effect of artemisia sieberi essence on the experimental ulcers of cutaneous leishmaniasis on balb/c mice. methods: this experimental research was performed to determine the effect of various concentrati...

statement of the problem: recurrent aphthous stomatitis (ras) is one of the most common lesions in the oral cavity. due to its multifactorial nature, there is no definitive treatment for ras. laser therapy is one of the suggested treatments to reduce patient’s discomfort. purpose: the purpose of the present clinical trial is to assess the effect of low and high level laser therapy on pain contr...

the purpose of the present randomized clinical trial study was to compare the effectiveness of bovine porous bone mineral (bpbm) with and without plasma rich in growth factors (prgf) in the treatment of mandibular class ii furcation defects.in seven patients, nine pairs of symmetric buccal or lingual mandibular class ii furcation defects were treated. in each patient, one defect received bpbm (...

it has been shown that the immunophilin ligands have the special advantage in spinal cord repair. in this study, the effects of cyclosporine a (csa) on functional recovery and histological outcome were evaluated following spinal cord injury in rats. after spinal cord hemisection in thirty six adult female sprague-dawley rats (200- 250 g), treatment groups received csa (2.5 mg/kg i.p.) at 15min ...

BACKGROUND Topical anesthetics, such as eutectic mixture of local anesthetics (EMLA) cream, can be applied to reduce pain before minor procedure. This trial evaluated EMLA as pretreatment for facial lacerations and compared pain, discomfort and overall satisfaction. METHODS This trial included consecutive emergency department patients ≥16 years of age who presented with simple facial lacerati...

Background: Statins, widely used cholesterol-lowering agents, have also been demonstrated to have anti-inflammatory and immunomdulatory effects. Objective: To evaluate the effects of atorvastatin in combination with Interferon-β in the treatment of multiple sclerosis (MS) in a randomized controlled clinical trial. Methods: Multiple sclerosis patients were randomized independently, in a double b...