Background and Aims: Giardia lamblia infection is a common cause of food and water-borne diarrhea in non-sanitary communities. Infections are common in children, particularly in child-care centers, backpackers, travelers, and homosexuals. Zinc is necessary for the immune system functions. Zinc deficiency is associated with acute diarrhea. Copper is essential for the production of red blood cell...

Trace elements are extremely important for normal metabolism. Copper is one of the trace metals which has important physiological function in maintaining thyroid activity. Copper is known to effect lipid metabolism. Increase in serum copper level is associated with decrease in concentration of total cholesterol (TC). Thyroid hormone binding transcription factors, which are essential for modulat...

Recent isotopic observations of animal samples indicate body accumulation of heavy zinc and light copper throughout life. This hypothesis has never been tested for humans, but the existence of a relationship between blood isotopic composition and age could be promising for age assessment methodologies. Dietary habits can also influence the blood zinc isotope composition, being an additional sou...

Zinc therapy has replaced penicillamine as first-line therapy for Wilson's disease. New guidelines reflect the paradigm shift in treatment that has occurred in recent years. In the old paradigm, Wilson's disease was seen as genetic disorder associated with the accumulation of copper in the liver and in other organs once the liver had become overloaded with copper. When left untreated, the disea...

to investigate uterine and serum copper (cu) and zinc (zn) concentrations variation duringthe bovine estrus cycle , 232 blood and genital tract samples were collected from the abattoir inurmia. the phase of the estrous cycle was determined by the examination of the ovaries and theuterine tonicity. of the 46 samples selected for use in the study, 13 were pro-estrus, 10 estrus, 8metestrus, and 15...

chronic hepatitis b virus (hbv) infection is a major liver disease worldwide and its clinical manifestations are linked to immune response. the purpose of this study was to evaluate the relationship between selenium, copper, and zinc in comparison with transaminase level in chronic hbv patients. serum samples of the hbv infected patients were obtained from tooba medical center, sari, iran. sixt...

febrile convulsions (fc) are the most common neurologic disorder in children 6-60 months of age. zinc (zn) and copper (cu) play role as cofactors in more than 300 enzymatic activities significantly. the aim of this study was to evaluate the relationship serum levels of zn and cu with seizure occurrence in febrile children. in this case-control study, 270 children with 6 month to 6 years were ev...

objective: multiple sclerosis (ms) is a chronic disease with prominent neurological and behavioral and psychiatric manifestations and unknown etiology which is demarcated with inflammation and destruction of white matter of brain and spinal cord and its replacement with gliotic tissue in young aged people and particularly females. the role of trace elements in multiple sclerosis is set forth in...

The "trace" elements copper and zinc are essential for life, and their role in the function of metalloproteins is well known. However, mounting evidence shows that these metals are also capable of modulating neuronal excitability under normal physiological conditions. They are present at high levels in the brain, are concentrated at nerve terminals, and are released at micromolar concentrations...