HCV-1 produces a novel protein, known as ARFP, F, or core+1. This protein is encoded by an open reading frame (ORF) that overlaps the core gene in the +1 frame (core+1 ORF). In vitro this protein is produced by a ribosomal frameshift mechanism. However, similar studies failed to detect the ARFP/F/core+1 protein in the HCV-1a (H) isolate. To clarify this issue and to elucidate the functions of t...

The active substrates in surface enhanced Raman scattering (SERS) spectroscopy were prepared through self-assembly of nanoparticles on functionalized glasses. Colloidal silver nanoparticles (Ag NPs) were prepared chemically in two different sizes by reduction of AgNO3 using trisodium citrate and sodium borohydride. Gold–silver core–shell nanoparticles were also prepared to compare between the o...

Purpose: A theory states that strong core stability allows athletes to fully transfer forces from the upper extremities to lower extremities, and finally to the ground. On the contrary, weak core stability causes alterations in transferring forces, reduces sport performance, and increases risk for injury, especially in the lower extremities. Therefore, the current study investigated the relatio...

abstractbackgroundentity. it is hypothesized to result from abnormal patellar tracking caused by altered motorcontrol. deficit in neuromotor control of the core may be a remote contributing factor to thedevelopment of pfp. application of reliable emg measures would be helpful to handle thistheory. therefore, the purpose of this study was to determine the test-retest reliability of thecore and v...

hepatitis c virus (hcv) is an important agent causing chronic liver infection, which often leads to liver cirrhosis and lethal hepatocellular carcinoma (hcc). at present, there is no effective hcv vaccine for prevention of hepatic disease and the standard treatment is neither economical nor fully effective in all the patients. however, vaccination based on structural and nonstructural proteins ...

HCV-1 produces a novel protein, known as ARFP, F, or core 1. This protein is encoded by an open reading frame (ORF) that overlaps the core gene in the 1 frame (core 1 ORF). In vitro this protein is produced by a ribosomal frameshift mechanism. However, similar studies failed to detect the ARFP/F/core 1 protein in the HCV-1a (H) isolate. To clarify this issue and to elucidate the functions of th...

Hepatitis C virus (HCV) infection is a major cause of chronic liver disease and hepatocellular carcinoma (HCC). HCV is an enveloped positivestranded RNA virus, belonging to the Flaviviridae family. The HCV genome produces a polyprotein precursor which is processed by proteases and yields at least 10 proteins. HCV possesses a second open reading frame (ORF) within the core gene, encoding an intr...

[1] Anomalous boundary layer structure at the core-mantle boundary (CMB) is investigated using a global set of broadband SKS and SPdKS waves from permanent and portable broadband seismometer arrays. SPdKS is an SKS wave that intersects the CMB at the critical angle for ScP, thus initiating a diffracted P wave (Pdiff) along the CMB at the core entry and exit locations. The waveshape and timing o...

ArvandHerd is a sequential satisficing planner that uses a portfolio consisting of LAMA and Arvand. This planner won the multi-core track of the 2011 International Planning Competition. In this paper, we describe the various components of ArvandHerd, the updates made for the 2014 competition, and the modifications that allow ArvandHerd to compete in the single-core sequential satisficing tracks.