BACKGROUND Corticosteroids seem to affect the functions of corneal endothelial cells directly in addition to their anti-inflammatory effect. CASE A 69-year-old man presented with blurred vision in his left eye and decreased visual acuity in both eyes. He had received anterior-posterior radial keratotomy for myopia in both eyes 40 years earlier. OBSERVATIONS Both eyes showed mild corneal str...

The possibility that the lymph vessels may proliferate and invade corneal tissue in association with a similar invasion of the blood vessels following the intraocular injection of alloxan monohydrate has already been presented. On that occasion the response of both the lymph and. blood vessels to external corneal damage was ignored. Moreover, no definitive proof teas presented to show that the ...

Objective: To study ocular manifestations in patients who were on long-term use of chlorpromazine. Methods: A retrospective observational case study was made. Three patients, who were diagnosed as Schizophrenia and on long-term use of chlorpromazine for more than 20 years, were examined retrospectively. The examinations included clinical history, physical examination, slit-lamp biomicroscopy, a...

We present 2 cases of anterior chamber ointment with evidence of progressive endothelial cell loss. In both cases, an anterior segment optical coherence tomography (OCT) was similar to an OCT of a tobramycin-dexamethasone ointment placed on a pen tip. An anterior segment OCT also demonstrated the direct contact of the globule with the corneal endothelium. A gas chromatography/mass spectrometry ...