PURPOSE New magnetic resonance imaging (MRI) methods can provide high spatial resolution images of the coronary artery wall, and statistically significant differences in coronary vessel wall thickness between atherosclerotic disease patients and control subjects have been shown. The aim of this study is to assess inter-study reproducibility (i.e., repeatability) of the cross-sectional 2D corona...

AIMS Limited information is available regarding the relationship between coronary vessel dominance and prognosis. Therefore, the purpose of this study was to determine the prognostic value of coronary vessel dominance in relation to significant coronary artery disease (CAD) in patients referred for computed tomography coronary angiography (CTA). METHODS AND RESULTS The study population consis...

BACKGROUND The extent of coronary collateral formation is a primary determinant of the severity of myocardial damage and mortality after coronary artery occlusion. Type 2 diabetes mellitus (T2DM) represents an important risk factor for impaired collateral vessel growth. However, the mechanism of reduced coronary collateralization in type 2 diabetic patients remains unclear. METHODS With the r...

The coronary vasculature is an essential vessel network providing the blood supply to the heart. Disruptions in coronary blood flow contribute to cardiac disease, a major cause of premature death worldwide. The generation of treatments for cardiovascular disease will be aided by a deeper understanding of the developmental processes that underpin coronary vessel formation. From an ENU mutagenesi...

Diabetes mellitus is a well-recognized risk-factor for coronary artery disease. It is known that diabetic patients have a two-to fourfold increased risk of mortality or morbidity for cardiovascular diseases compared with the general population. Further, many diabetic patients with coronary heart disease have severe diseased coronary arteries: multi-vessel disease and/or severe stenosed vessel(s...

INTRODUCTION Coronary vessel perforation is one of the most feared complications of coronary angioplasty. The treatment of this complication relies mostly on the implantation of covered stents. However, due to their design, covered stents are difficult to advance in a tortuous or calcified vessel. CASE PRESENTATION We present a case of a grade III coronary perforation in which the double guid...

Sixteen patients, 10 with significant three-vessel coronary artery disease (>50% occlusion of each vessel) and six without coronary disease, had nutrient myocardial blood flow, cardiac output, pressure time/ min and arterial pressure determinations at rest, with atrial pacing and with right atrial pacing plus nitroglycerin. In the patients with coronary disease, nutrient myocardial blood decrea...

OBJECTIVES We examined whether delayed-enhancement cardiovascular magnetic resonance (DE-CMR) coronary artery wall imaging correlated with atherosclerosis detected by using multislice computed tomography (MSCT) and quantitative coronary angiography (QCA). BACKGROUND The use of DE-CMR coronary vessel wall imaging may provide a noninvasive method to assess diseased coronary vessel walls. METH...

background: stenting is currently the standard of care in percutaneous coronary intervention (pci). whether young patients remain at increased risk after pci in the present stent era has not been investigated widely. we evaluated angiographic characteristics and short- and mid-term outcomes in patients younger than 40 years of age who underwent pci. methods: from april 2003 to march 2005, prosp...