A prospective observational cohort study was conducted in 302 human immunodeficiency virus-infected patients who had a CD4 T-cell count <100 cells/µL and negative serum cryptococcal antigen initiating antiretroviral therapy in a resource-limited setting. During 2-year follow-up, there were no differences of survival rates and occurrences of newly diagnosed cryptococcosis between patients with a...

1791. Evaluating Cryptococcal Antigen Lateral Flow Assay by Fingerstick Whole Blood in HIV-Infected Persons with Meningitis Darlisha Williams, MPH; Kiiza Tadeo,; Sruti Velamakkani,; Reuben Kiggundu,; David Meya, MMed; Joshua Rhein, MD; David Boulware, MD, MPH; Center for Infectious Diseases & Microbiology Translational Research, University of Minnesota, Minneapolis, MN; Infectious Disease Insti...

BACKGROUND Many deaths from cryptococcal meningitis (CM) may be preventable through early diagnosis and treatment. An inexpensive point-of-care (POC) assay for use with urine or a drop of blood would facilitate early diagnosis of cryptococcal infection in resource-limited settings. We compared cryptococcal antigen (CRAG) concentrations in plasma, serum, and urine from patients with CM, using an...

An immunocompetent 5 year-old girl presented with pyrexia of unknown origin associated with headache. Initial investigations showed leukocytosis and an increased erythrocyte sedimentation rate. A Widal-Weil Felix test, blood film for malarial parasites, mycoplasma IgM antibody, cultures from blood and urine, full blood picture, Mantoux test, and chest x-ray were all negative. A lumbar puncture ...

To cite: El-Kersh K, Chaddha U, Cavallazzi R, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2014207005 DESCRIPTION Endobronchial ultrasound-guided fine-needle aspiration (EBUS-FNA) is a minimally invasive technique that allows cytological and histological examination of the tissue sampled from mediastinal lymph nodes under real-time ultrasound guidance. E...