نتایج جستجو برای: cryptococcal antigen

تعداد نتایج: 202686  

Journal: :iranian journal of public health 0
f zaini m safara p kordbacheh m pezeshki b beheshti

cryptococcosis has become the fourth leading life-threatening opportunistic infection in patients with aids, but also occurs in non-aids patients. in view of the increasing numbers of infection during last decade in iran, use of rapid, sensitive and specific test for diagnosis of cryptococcal disease has become important than ever. we aimed to produce the reagents for latex cryptococcal antigen...

2014
Kinanga A Magambo Samuel E Kalluvya Shikha W Kapoor Jeremiah Seni Awilly A Chofle Daniel W Fitzgerald Jennifer A Downs

BACKGROUND Detection of subclinical cryptococcal disease using cryptococcal antigen screening among HIV-positive individuals presents a potential opportunity for prevention of both clinical disease and death if patients with detectable cryptococcal antigen are identified and treated pre-emptively. Recently developed point-of-care cryptococcal antigen tests may be useful for screening, particula...

Journal: :Journal of clinical microbiology 2004
Diane C McFadden Oscar Zaragoza Arturo Casadevall

The stability of cryptococcal antigen from Cryptococcus neoformans serotype A and D strains at different temperatures in serum and other solvents was studied. Samples stored at -20 or 4 degrees C had equivalent stabilities as measured by the Premier Cryptococcal Antigen kit and the Cryptococcal Antigen Latex Agglutination System (CALAS) kit. However, using the Premier Cryptococcal Antigen kit, ...

Journal: :Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2009
Joseph N Jarvis Stephen D Lawn Monica Vogt Nonzwakazi Bangani Robin Wood Thomas S Harrison

BACKGROUND Cryptococcal meningitis is a leading cause of death in patients with acquired immunodeficiency syndrome and contributes substantially to the high early mortality in antiretroviral treatment (ART) programs in low-resource settings. Screening for cryptococcal antigen in patients who enroll in ART programs may identify those at risk of cryptococcal meningitis and permit targeted use of ...

Journal: :acta medica iranica 0
oghomwen favour osazuwa department of medical microbiology, university of benin teaching hospital, pmb 1111.benin city, nigeria. and federal capital territory administration, medical microbiology /pepfar laboratory, wuse district hospital, pmb 24, abuja, nigeria. osilume dirisu department of medical microbiology, university of benin teaching hospital, pmb 1111.benin city, nigeria. and lahor medical research laboratory, iwogban, benin city, nigeria. evbaguehita okuonghae department of medical microbiology, university of benin teaching hospital, pmb 1111.benin city, nigeria.

cryptococcus neoformans is the most incriminated fungal pathogen causing meningitis in acquired immune deficiency syndrome (aids) patients, and is known to constitute a major cause of deaths in aids patients. this study aimed to determine the sero-prevalence and effect of cd4 count on seropositivity for cryptococcus neoformans antigen (crag) in antiretroviral- naïve (art-naïve) aids patients. t...

2017
Diego H. Cáceres Alejandra Zuluaga Ángela M. Tabares Tom Chiller Ángel González Beatriz L. Gómez

A Lateral Flow Assay to detect cryptococcal antigen (CrAg® LFA) in serum and cerebrospinal fluid for the rapid diagnosis of cryptococcosis was evaluated. A retrospective validation was performed. Sensitivity and specificity of the CrAg® LFA was 100%. High concordance (kappa index=1.0) between Cryptococcal Antigen Latex Agglutination System (CALAS®) and CrAg® LFA was observed. CrAg® LFA showed h...

Journal: :Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2004
Cristina Mussini Patrizio Pezzotti José M Miró Esteban Martinez Juan Carlos Lopez Bernaldo de Quiros Paola Cinque Vanni Borghi Andrea Bedini Pere Domingo Pedro Cahn Philippe Bossi Andrea de Luca Antonella d'Arminio Monforte Mark Nelson Nneka Nwokolo Silvia Helou Ricardo Negroni Gaia Jacchetti Spinello Antinori Adriano Lazzarin Andrea Cossarizza Roberto Esposito Andrea Antinori Judith A Aberg

We conducted a retrospective, multicenter study evaluating the safety of discontinuing maintenance therapy for cryptococcal meningitis after immune reconstitution. Inclusion criteria were a previous definitive diagnosis of cryptococcal meningitis, a CD4 cell count of >100 cells/microL while receiving highly active antiretroviral therapy (HAART), and the subsequent discontinuation of maintenance...

2014
Richard Kwizera Joyce Nguna Agnes Kiragga Jesca Nakavuma Radha Rajasingham David R. Boulware David B. Meya

BACKGROUND Cryptococcal meningitis can best be diagnosed by cerebrospinal fluid India ink microscopy, cryptococcal antigen detection, or culture. These require invasive lumbar punctures. The utility of cryptococcal antigen detection in saliva is unknown. We evaluated the diagnostic performance of the point-of-care cryptococcal antigen lateral flow assay (CrAg LFA) in saliva. METHODS We screen...

2014
Ahmad Rizal Ganiem Agnes Rengga Indrati Rudi Wisaksana Hinta Meijerink Andre van der Ven Bachti Alisjahbana Reinout van Crevel

INTRODUCTION Previous studies, mostly from Africa, have shown that serum cryptococcal antigenemia may precede the development of cryptococcal meningitis and early death among patients with advanced HIV infection. We examined cryptococcal antigenemia as a risk factor for HIV-associated mortality in Indonesia, which is experiencing a rapidly growing HIV epidemic. METHODS We included ART-naïve H...

Journal: :Journal of clinical microbiology 2005
Hongzhou Lu Yingjie Zhou Youkuan Yin Xiaozhang Pan Xinhua Weng

For a total of 29 non-human immunodeficiency virus 1 cryptococcal meningitis cases, titer changes in the latex agglutination test before and after therapy were reviewed along with clinical manifestations, laboratory findings, and therapy regimens. The cryptococcal antigen titer decreased for every case after therapy and was correlated to fungal clearance as defined by fungus smear and/or cultur...

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