OBJECTIVE Adaptive social functioning is severely impeded in depressive and anxiety disorders, even after remission. However, a comprehensive overview is still lacking. METHOD Using data from the Netherlands Study of Depression and Anxiety (NESDA), behavioural (network size, social activities, social support) and affective (loneliness, affiliation, perceived social disability) indicators of s...

BACKGROUND In Japan and Asia, few studies have been done of physical and sexual abuse. This study was aimed to determine whether a history of childhood physical abuse is associated with anxiety, depression and self-injurious behavior in outpatients with psychosomatic symptoms. METHODS We divided 564 consecutive new outpatients at the Department of Psychosomatic Medicine of Kyushu University H...

Background: Panic disorder with agoraphobia (PDA) co-occurs highly with depression. Greater panic symptoms, agoraphobic avoidance, comorbidity and anxiety sensitivity have all been linked to depressive symptoms in PDA. Psychotherapy research has historically linked prognostic and process expectationsto symptom severity. However, no study has explored the relationship of expectancies and depress...

OBJECTIVE The authors sought to determine whether personality disorders diagnosed during a depressive episode have long-term outcomes more typical of those of other patients with personality disorders or those of patients with noncomorbid major depression. METHOD The authors used 6-year outcome data collected from the multisite Collaborative Longitudinal Personality Disorders Study (CLPS). Di...

BACKGROUND Though an important percentage of patients with chronic hepatitis C virus (HCV) undergoing interferon (IFN) therapy develop depressive symptoms, the role of the IFN system in the pathogenesis of depressive disorders is not well understood. METHODS 50 patients with HCV infection were treated with standard combination therapy (pegylated IFN-α2a/ribavirin). IFN-induced gene expression...

BACKGROUND Mental disorders are associated with increased mortality, but population-based surveys with reliable diagnostic procedures controlling for somatic health status are scarce. AIMS To assess excess mortality associated with depressive, anxiety and alcohol use disorders and the principal causes of death. METHOD In a nationally representative sample of Finns aged 30-70 years, psychiat...

chronic arsenic poisoning (arsenicosis) is a global health risk, and it has been reported to improve the fitness, especially in altitudinal sickness in therapeutic dose. scarcity of systematic study on psychiatric co-morbidities in arsenicosis motivated us to conduct this research. the aim of this study was to estimate the co-morbid psychiatric disorders in patients with arsenicosis and to exam...

OBJECTIVES To investigate a) whether childhood adversity predicts adult-onset asthma; b) whether early-onset depressive/anxiety disorders predict adult-onset asthma; and c) whether childhood adversity and early-onset depressive/anxiety disorders predict adult-onset asthma independently of each other. Previous research has suggested, but not established, that childhood adversity may predict adul...

Objective: Evaluation of the effectiveness of progressive relaxation (PR) versus autogenic training (AT) in the complementary treatment of anxiety disorders and depressive disorders implemented at the start of outpatient psychotherapy. Method: Randomized controlled trials including unselected samples of 60 adult patients with anxiety disorders and 60 adult patients with depressive disorders. In...