Effects of histatin-derived peptides immobilization by tresyl chloride-activation technique for MC3T3-E1 cellular responses on titanium (Ti) were evaluated. cultured sandblasted and acid-etched Ti disks immobilized with peptides, including histatin-1, JH8194, mixed histatin-1 JH8194. Surface topography morphology examined using a scanning electron microscope. Elemental composition conformationa...

Development of human bodies, organs, and tissues contains numerous steps of cellular differentiation including an initial zygote, embryonic stem (ES) cells, three germ layers, and multiple expertized lineages of cells. Induced pluripotent stem (iPS) cells have been recently developed using defined reprogramming factors such as Nanog, Klf5, Oct3/4 (Pou5f1), Sox2, and Myc. This outstanding innova...

O 6 Methyguanine-DNA methyl transferase is a very critical enzyme in a cell. It protects cells from carcinogens and protects the tumour cells from chemotherapeutic agents. It is considered a unique DNA-repair enzyme and thought to act alone to repair alkyl lesions of DNA. This protein however, is without a nuclear localization signal and yet found to be nuclear. In this study, utilising human C...

micrornas (mirnas) represent a class of small non-coding rna molecules that regulate gene expression at the post-transcriptional level. they play a crucial role in diverse cellular pathways. ionizing radiation (ir) is one of the most important treatment protocols for patients that suffer from cancer and affects directly or indirectly cellular integration. recently it has been discovered that mi...

The placenta is a temporary fetomaternal organ capable of supporting fetal growth and development during pregnancy. In particular, abnormal development and dysfunction of the placenta due to cha nges in the proliferation, differentiation, cell death, and invasion of trophoblasts induce several gynecological diseases as well as abnormal fetal development. Autophagy is a catalytic process that ma...