Pasteurella multocida (P. multocida) is an important pathogen of various domestic animals. The outer membrane proteins (OMPs) play a major role in pathogenesis and immunogenicity of P. multocida. The aim of the study was to develop indirect enzyme linked immuno sorbant assay (ELISA) based on OMPs to ascertain the antibody titers in animals post-infection or to gauge the potency of vaccine. The ...

We examined the relationship between analytical sensitivity, precision at the lower limit of the reference interval, and diagnostic performance in hyperthyroidism for one radioimmunoassay and five immunometric assay kits for thyrotropin. The analytical sensitivity of these kits extended from 0.05 to 1.56 milli-int. units/L. Diagnostic efficiencies of the immunometric assays, in discriminating b...

Polymerase chain reaction (PCR)-based testing is being widely implemented for diagnostic purposes. The PCR technique is generally considered to be both analytically sensitive (i.e., detects small quantities of a substance) and analytically specific (i.e., few cross reactions). There are few studies, however, of diagnostic sensitivity and specificity (i.e., the likelihood of correctly identifyin...

the fna (fine needle aspiration) procedure is simple, inexpensive, available and a safe method for the diagnosis of a neck mass. fna has numerous advantages over open surgical biopsies as an initial diagnostic tool; therefore we decided to compare the accuracy of this method with open biopsy. this retrospective as well as descriptive study comparing preoperative fna results with existing data i...

objectives: this study sought to assess the diagnostic accuracy of cone beam computed tomography (cbct) with different voxel sizes and intraoral digital radiography with photostimulable phosphor (psp) plate for detection of periapical (pa) bone lesions. materials and methods: in this ex vivo diagnostic study, one-millimeter defects were created in the alveolar sockets of 15 bone blocks, each wi...

introduction: based on the existing studies, measuring serum level of immunoglobulin for making decisions regarding prescription of tetanus prophylaxis seems logical and cost effective. therefore, the present study was done with the aim of evaluating the diagnostic accuracy of tetanus quick stick (tqs) in comparison with elisa method in this regard. methods: the present diagnostic accuracy stud...

Background: Intra-operative molecular diagnostic assays are currently used for the detection of lymph node metastases. The objective of this study was to find new biomarkers to improve diagnostic accuracy in the detection of metastatic axillary lymph nodes in breast cancer patients. Methods: We applied an absolute quantitative real-time RT-PCR to quantitate the expression of CK19, KLK11, and CL...