Aqueous and alcoholic extracts of Vitis indica were tested for diuretic activity in rats. The parameters studied on individual rats were body weight before and after test period, total urine volume, urine concentration of Na+,Ka+ and Cr. In the present study, alcoholic and aqueous extracts of Vitis indica leaves (200 mg/kg body weight) shows increase in urine volume, cationic and anionic excret...

The diuretic potential of methanolic extract of whole plant of Jussiaea suffruticosa was evaluated in male albino rats. The volume of urine, urinary concentration of sodium, potassium and chloride ions was the tested parameters of the study. Furosemide (100 mg/kg) was used as standard. Methanolic extract was tested in dose levels of 200 and 400 mg/kg. The methanolic extract at 400 mg/kg dose le...

BACKGROUND In the Ethiopian traditional medicine, the leaves of Ajuga remota B. (Local name, Armagusa) is used in the treatment of hypertension. Since this claim has not been investigated scientifically, the aim of the present study was to evaluate the diuretic potential of the aqueous and 80% methanol extracts of the leaves of Ajuga remota in mice after acute oral administration. METHODS Adu...

Achyranthes aspera Linn (Amaranthaceae), commonly known as Apamarga in Ayurveda and is found as a weed that has been traditionally used for a number of ailments. The plant is indigenously used as diuretic, spermicidal, anti-allergic, cardiovascular, nephroprotective, antiparasitic, hypoglyceamic, analgesic and antipyretic. In the present study the methanolic extract of whole plant of Achyranthe...

Mechanoreceptors and chemoreceptors have been identified inside the kidney, but their functional role is still largely unclear. The aim of this study was to investigate whether changes in urine output could modify the discharge rate of renal afferent fibers. Experiments were performed in anesthetized cats in which afferent renal nerve activity (ARNA) was recorded by standard electrophysiologica...

The present study was undertaken to establish the diuretic activity of ethanol and aqueous extract of dried leaves of Garcinia cambogia in rats. Aqueous and ethanol extracts of leaves were administered to experimental rats orally at doses of 100 and 200 mg/kg and compared with furosemide (20 mg/kg, intraperitoneally) as the standard. The parameters measured for diuretic activity were total urin...

Purpose: The aim of the present study was to investigate the diuretic activity of ethanolic extracts and its fractions of Aegle marmelos fruit in experimental models. Ethanolic extracts and its fractions of Aegle marmelos ripe fruit were administered to experimental rats intraperitonealy at doses of 300, 400 and 500 mg/kg i. p. Control group received only normal saline (25ml/kg) through intrape...

Introduction: It has been suggested that calculation of differential renal function (DRF) using 99mTc-DMSA may lead to overestimation of the function of an obstructed kidney. The aim of this study was to evaluate the effect of diuretic administration on the determination of DRF using 99mTc-DMSA scintigraphy in patients with dilated pelvis. Methods: Thirty three patients, aged from 2 month...

Purpose: The present study was undertaken to investigate diuretic effect of aqueous and methanol extracts of the dried seeds of erythrina indica in normal rats. Method: Aqueous and methanol extracts of erythrina indica seeds were administered to experimental rats orally at doses of 25 and 30 ml/kg p.o. Furosemide (10 mg/kg) was used as positive control in the study. The diuretic effect of the e...

There is growing interest in the health benefits of herbs and botanicals. In line with this there are an increasing number of published articles claiming that plants or plant-derived actives may function as mild diuretic agents. Diuretics are substances that act within the kidney and promote the loss of fluid from the body. A large majority of this research has determined the degree of clinical...