incorporation of functional foods and nutraceuticals such as carotenoids which suffer from poor water solubility and low bioavailability into nano-sized delivery systems can improve their solubility, stability and oral bioavailability. the aim of this study was to prepare β-carotene nanodispersion and investigate the effects of preparation parameters by means of response surface methodology usi...

A critical and often overlooked aspect underlying the design and consequent realisation of an artifact is its design intent. Given the highly distributed and diverse nature of workflows in today’s design environments, the need to have a shared understanding of the design intent, to enable effective communication and coordination between the development teams is crucial. In this paper we present...

When the number of data used for an identification experiment is small, the data contain transient effects and these effects contribute to the accuracy of the identified model. Consequently, when designing the optimal input signal for an identification experiment in the case of small data set, these transient effects have to be taken into account. In this paper, we present a methodology for opt...