Abstract Dual labeled contrast agents could provide better complementary information for bioimaging than available solely from a single modality. In this paper we investigate the suitability of Yb3+ and Er3+-doped BaYF5 upconversion nanoparticles (UCNPs) as both optical X-ray micro computed tomography (?CT) agents. Stable, aqueous UCNP dispersions were synthesised using hydrothermal method with...

The purpose of this study was to evaluate treatment patterns, outcome and prognosticators for patients with leptomeningeal metastases from solid tumor. Medical records of 80 patients from January 1, 2004 to May 31, 2011 were retrospectively reviewed. Most frequent site of origin was the lung (59%) followed by the breast (25%). Most patients were treated with intrathecal chemotherapy (90%) and/o...

Positron emission tomography (PET) has become one of the major tools for the in vivo localisation of positron-emitting tracers and now is performed routinely using (18)F-fluorodeoxyglucose (FDG) to answer important clinical questions including those in cardiology, neurology, psychiatry, and oncology. The latter application contributed largely to the wide acceptance of this imaging modality and ...

Most pathological conditions elicit changes in the tissue optical response that may be interrogated by one or more optical imaging modalities. Any single modality typically only furnishes an incomplete picture of the tissue optical response, hence an approach that integrates complementary optical imaging modalities is needed for a more comprehensive non-destructive and minimally-invasive tissue...

Designing appropriate materials and activities to enhance vocabulary learning is one of the primary goals of language courses. Among the claims about efficient pedagogical tasks is the Involvement Load Hypothesis (Laufer & Hulstijn, 2001) according to which vocabulary development is contingent on the amount of cognitive process a task involves. Building on the previous research on this hypothes...

Cross-modal retrieval has become an active study field with the expanding scale of multimodal data. To date, most existing methods transform data into a common representation space where semantic similarities between items can be directly measured across different modalities. However, these typically suffer from following limitations: 1) They usually attempt to bridge modality gap by designing ...

In this paper, we introduce a novel problem of audio-visual event localization in unconstrained videos. We define an audio-visual event as an event that is both visible and audible in a video segment. We collect an Audio-Visual Event (AVE) dataset to systemically investigate three temporal localization tasks: supervised and weakly-supervised audio-visual event localization, and cross-modality l...

Age-related deficits in cognitive and sensory function can result in increased distraction from background sensory stimuli. This randomized controlled trial investigated the effects of a cognitive training intervention aimed at helping healthy older adults suppress irrelevant auditory and visual stimuli. Sixty-six participants received 8 weeks of either the modality-specific attention training ...