BackgroundThe consequences of COVID-19 in those who recover from acute infection requiring hospitalisation have yet to be clearly defined. We aimed describe the temporal trends respiratory outcomes over 12 months patients hospitalised for severe and investigate associated risk factors.MethodsIn this prospective, longitudinal, cohort study, admitted hospital did not require mechanical ventilatio...

drug abuse is a problem that causes a wide array of social, emotional, and physical problems and involves both patients and the society. helping the addicted has always been a priority for physicians and especially psychiatrists. the purpose of this prospective study was to compare the effects of methadone and naltrexone in general well-being of patients undergoing these treatments.forty-six pa...

INTRODUCTION Pharmaco-economic data on the management of knee osteoarthritis (OA) with intra articular hyaluronic acid (IA HA) viscosupplementation is limited. We contrasted IA HA with non-steroidal anti-inflammatory drugs (NSAIDs). METHODS Observational, prospective and multicenter study comparing treatments of knee OA costs and efficacy with either NSAIDs alone, or hyaluronic acid (Arthrum ...

The purpose of this study was to identify whether a past history of childhood sexual abuse is a risk factor for repeated Deliberate Self-Harm (DSH). The study was a 6-month prospective study of 178 patients responsible for 190 consecutive cases of DSH seen during a 3-month censoring period. Patients were identified by review of the in-patient and accident and emergency (A&E) records of all case...

We report a trial of minocycline in people with relapsingremitting multiple sclerosis (RRMS) that evaluates safety and estimates its effect on magnetic resonance imaging (MRI). Ten subjects with active RRMS received oral minocycline 100mg twice daily for 6 months after a 3-month run-in period. A 30-month treatment extension is ongoing. Clinical and laboratory assessments were completed at enrol...

Serial assessments of cognition, mood, and disability were carried out at nine month intervals over a 54 month period on a cohort of 87 patients with Parkinson's disease (PD) and a matched cohort of 50 control subjects. Dementia was diagnosed from data by rigorously applying DSM-III-R criteria. Initially, 6% (5/87) PD patients were demented, compared with none of the 50 control subjects. A furt...