INTRODUCTION Dual antiplatelet therapy is standard treatment following percutaneous coronary intervention (PCI) and stenting. However, such therapy increases the risk of upper gastrointestinal bleeding (UGIB). The risk factors of UGIB are well-documented and proton pump inhibitor (PPI) treatment reduces the risk. The aim was to describe the prevalence of risk factors of UGIB in dual antiplatele...

OBJECTIVE To assess prevalence of Helicobacter pylori infection, reasons for referral for gastroscopy, and clinical findings of gastroscopy in a symptomatic First Nations population in northwestern Ontario from 2009 to 2011. DESIGN Three hundred four hospital charts of symptomatic patients who underwent upper endoscopy between June 2009 and March 2011 were reviewed. SETTING Meno Ya Win Heal...

BACKGROUND/AIMS Atypical symptoms are common in gastroesophageal reflux disease (GERD). Patients with non-erosive reflux disease (NERD) and erosive reflux disease (ERD) exhibit different clinical characteristics and responses to acid suppression treatment. We aimed to compare atypical characteristics in patients with NERD and ERD. We also investigated the presence of histological esophagitis in...

seen in the primary care setting. We believe, however, that our findings would need to be assessed in the primary care setting before implementation is considered. Contributors: See bmj.com Funding: No pharmaceutical company or other commercial entity provided funding or other resources for the study. Competing interests: None declared. Ethical approval: The local ethics committee approved the ...

Neurological diseases are common in inflammatory bowel disease (IBD) patients, but their exact prevalence is unknown. Method: We prospectively evaluated the presence of neurological disorders in 121 patients with IBD [51 with Crohn’s disease (CD) and 70 with ulcerative colitis (UC)] and 50 controls (gastritis and dyspepsia) over 3 years. Results: Our standard neurological evaluation (that inclu...

Background/Aims Gastric motility abnormalities have been considered to be pathophysiological features of functional dyspepsia (FD) that are closely related to dyspepsia symptoms, especially postprandial distress syndrome (PDS). The aims of this study are to (1) investigate the prevalence of gastric motility disorders and (2) evaluate the association between gastric motility abnormalities and dy...

Objectives: To determine the prevalence of lactose intolerance in patients with functional dyspepsia and to document the association of changing in duodenal villi in Thai patients with lactose malabsorption by using breath hydrogen excretion test. Patients and Methods: Functional dyspepsia patients who had no history of milk allergy and underwent gastroduodenoscopy. Two mucosal biopsy specimens...

BACKGROUND The purpose was to evaluate the overlap frequency of irritable bowel syndrome (IBS), gastroesophageal reflux disease (GERD), and overactive bladder syndrome (OBS), as well as other gastrointestinal and systemic symptoms, in functional dyspepsia (FD). Additionally, we sought to determine whether adult Rome III FD subtypes were uniquely related to overlap syndromes or symptoms. METHO...

The aim of the study was to determine the frequency of functional and organic dyspepsia and possible predictors for organic dyspepsia in coronary artery disease (CAD) patients. The 150 patients (109 men; mean age 62.61 +/- 10.23 yr) undergoing coronary artery by-pass grafting because of stable pectoral angina due to significant CAD were enrolled in the study. Dyspepsia was determined by the exi...

Dyspepsia is a poorly understood term that is used to describe symptoms that originate in the upper gastrointestinal tract. There is increasing evidence that Helicobacter pylori infection plays an aetiological role in some forms of dyspepsia. H. pylori infection is more common in dyspeptic patients than asymptomatic controls. Clinical trials of the benefit of H. pylori eradication therapy in no...