BACKGROUND Ectopic pregnancy (EP) is one of the most dangerous complications of pregnancy and without prompt diagnosis and treatment, it could become a major cause of maternal morbidity and mortality. OBJECTIVES In this randomized controlled study, we compared single and double dose of methotrexate (MTX) therapy in the treatment of ectopic pregnancy. PATIENTS AND METHODS This study was perf...

OBJECTIVE To assess occurrence of severe maternal complications associated with ectopic pregnancy (EP). METHOD A multicenter cross-sectional study was conducted, with prospective surveillance of potentially life-threatening conditions (PLTC), maternal near miss (MNM), and maternal death (MD). EP complications, patient sociodemographic/obstetric characteristics, and conditions of severity mana...

Ectopic pregnancy (EP) remains a major gynecological emergency and is a cause of morbidity or even mortality in women. As a consequence, top citation analysis of EP research in database of the Science Citation Index Expanded is needed to assess the publication trends of leading countries/territories and institutes as well as the research hotspots of EP. A total of 4881 articles relevant to EP w...

Regarding the false negative results of culdocentesis, it is believed that the protocol of B-hCG, sonography, D&C and free use of laparoscopy gives more reliable information to the physician than the protocol of B-hCG, sonography and culdocentesis. We used the former protocol on 50 patients suspected of having ectopic pregnancy. The most common diagnoses were EP (48%) and PID (16%), respec...

Dear Editor Ectopic pregnancy (EP) is the most important cause of maternal death in the first trimester accounting for 9 13% of all pregnancy-related deaths (1). Despite the use of transvaginal sonography and high sensitive quantitative beta-hCG assays for diagnosis, nearly 40-50% of all EPs may be initially misdiagnosed (2). Therefore, several biomarkers have been investigated for early diagno...

OBJECTIVE To evaluate the plasma creatine phosphokinase (CPK) level after injection of methotrexate (MTX) as a predictor of treatment success in ectopic pregnancy (EP). MATERIALS AND METHODS One hundred women treated with single dose of methotrexate for ectopic pregnancy were evaluated in a prospective study, for CPK and ß-subunit of human chorionic gonadotropin (ß-hCG) levels. They received ...

OBJECTIVE To establish whether the finding of perihepatic adhesions (PHAs) at laparoscopy for ectopic pregnancy (EP) is associated with poor perioperative and reproductive outcomes. METHODS A retrospective cohort study was undertaken of all cases of EP managed surgically at a teaching hospital in northeast London in 2003-2013. Data for symptoms, reproductive history, ultrasonography findings,...

Ectopic pregnancy occurs in 1–2% of pregnancies and is the leading cause of maternal mortality in the first trimester; accounting for up to 15% first trimester deaths. There is a worldwide consensus regarding the use of transvaginal ultrasound (TVS) and (serial) quantitative serum human chorionic gonadotrophin (hCG) levels in the diagnosis of ectopic pregnancy. Diagnosis can be straightforward ...

Abstract Introduction: One of the contributing factors in ectopic pregnancy is genital infection. The self-treatment of genital infections is a common practice that results in infectious diseases, microbial resistance, and no patient recovery. Objective: This study aimed to determine the relationship between the self-treatment of genital infection and ectopic pregnancy. Materials and Method...