نتایج جستجو برای: efflux pumps
تعداد نتایج: 29824 فیلتر نتایج به سال:
Fluoroquinolones are widely used in both community and hospital settings. E.coli exhibits multiple resistant mechanisms; recent studies showed that multidrug resistant (MDR) efflux mechanism is most common. The effects of MDR inhibitors of the RND efflux pumps, Reserpine 25 μg/ml and MC 207, 110 (Phe-Arg-beta-naphthylamide (PaβN), Sigma) 25 μg/ml, on the MIC of fluoroquinolones for clinical iso...
AcrAB-TolC is the paradigm resistance-nodulation-division (RND) multidrug resistance efflux system in Gram-negative bacteria, with AcrB being the pump protein in this complex. We constructed a nonfunctional AcrB mutant by replacing D408, a highly conserved residue essential for proton translocation. Western blotting confirmed that the AcrB D408A mutant had the same native level of expression of...
Alpha-tocopherol is one the most abundant and biologically active isoforms of vitamin E. This compound is a potent antioxidant and one of most studied isoforms of vitamin E. Vitamin D3 (cholecalciferol) is an important nutrient for calcium homeostasis and bone health, that has also been recognized as a potent modulator of the immune response. Methicillin-resistant Staphylococcus aureus (MRSA) i...
ABSTRACT Background and Objectives: Pseudomonas aeruginosa is an important non-fermenting gram-negative hospital-acquired pathogen. Treatment of P. aeruginosa infections has become more challenging due to overexpression of efflux pumps. The aim of the present study was to apply in silico analysis to evaluate the structure of the effl...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید