Objective: Ethyl pyruvate (EP) is a molecule with antioxidant, anti-inflammatory, and anti-apoptotic features. The present study investigates EP's effects on behavioral biochemical alterations induced by immobilization (IM) stress. 
 Methods: In this outcome, 45 male BALB/c mice were separated into five groups [CONT (control), IM, IM+EP, EP, IM+F (fluoxetine)]. IM applied had 6 hours of st...

Background Infertility and fertility decline are quite a conundrum for medicine, rampant among 10-15 percent of couples. In about 40 percent of cases, men are the main culprit. Since sperm production disorders are the focal cause of man infertility, insights into these disorders and taking action to ameliorate the situation is quite vital. The current study concentrates on infertility due to sp...

Halmann, M. (The Israel Institute for Biological Research, Ness Ziona) and A. Keynan. Stages in germination of spores of Bacillus licheniformis. J. Bacteriol. 84:1187-1193. 1962.-This work defines conditions under which the first biochemical step in germination of spores (the so-called trigger reaction) could be studied separately from subsequent steps in germination. Although the initiation of...

Sucrose is an abundant, cheap, and renewable carbohydrate which makes it attractive feedstock for the biotechnological production of chemicals. Escherichia coli W, one few safe E. strains able to metabolize sucrose, was examined pyruvate. The repressor csc regulon deleted in W expressing a variant E1 component pyruvate dehydrogenase complex, these were screened shake flask culture formation fro...

The aim of the present study was to assess the protective effect of ethyl pyruvate (EP) on sperm quality parameters, testosterone level and malondialdehyde (MDA) in phenylhydrazine (PHZ) treated mice. For this purpose, 32 NMRI mice with the age range of 8 to 10 weeks, weight average 26.0 ± 2.0 g, were randomly divided into four equal groups. The control group (1) received normal saline (0. 1 mL...

The results of this study of the effect of temperature on the respiratory mechanism of five stenothermophilic bacteria may be summarized as follows:- 1. The respiratory mechanism and its various components of the stenothermophilic bacteria were found to function at temperatures below the minimum temperature for growth of these organisms. In every case the rates of the individual reactions invol...

BACKGROUND Demyelination and axonal damage are critical processes in the pathogenesis of multiple sclerosis (MS). Oxidative stress and pro-inflammatory cytokines elicited by inflammation mediates tissue damage. METHODS/PRINCIPAL FINDINGS To monitor the demyelination and axonal injury associated with microglia activation we employed a model using cerebellar organotypic cultures stimulated with...