Restricted maximum likelihood (REML) is now well established as a method for estimating the parameters of the general Gaussian linear model with a structured covariance matrix, in particular for mixed linear models. Conventionally, estimates of precision and inference for fixed effects are based on their asymptotic distribution, which is known to be inadequate for some small-sample problems. In...

Determining the genetic structure of populations is becoming an increasingly important aspect of genetic studies. One of the most frequently used methods is the calculation of F-statistics using an Analysis of Molecular Variance (AMOVA). However, this has the drawback that the population hierarchy has to be known a priori. Therefore, the population structure is often based on the results of a c...

abstract background: conflict is the lack of agreement and disagreement between the two men, and behavioral maladjustment or objectives that are in opposition to the other. destructive conflicts are incidents imposed on one or more than one member of the family or the whole family and affect on them. the purpose of this research is to study the effect of solution - focused short-term approach o...

In this paper we introduce three natural “score statistics” for testing the hypothesis that F (t0) takes on a fixed value in the context of nonparametric inference with current status data. These three new test statistics have natural intepretations in terms of certain (weighted) L2 distances, and are also connected to natural “one-sided” scores. We compare these new test statistics with an ana...

In various statistical model, such as density estimation and estimation of regression curves or hazard rates, monotonicity constraints can arise naturally. A frequently encountered problem in nonparametric statistics is to estimate a monotone density function f on a compact interval. A known estimator for density function of f under the restriction that f is decreasing, is Grenander estimator, ...

We consider the problem of computing the power of some usual F transforms of the Wilks U, Hotelling-Lawley T, and Pillai V statistics for testing H0: CBA = Œ0 under the multivariate general linear model, Y = XB + ‰ , where the rows of ‰A are taken as independent N(0, Í) random vectors. Keeping all these matrices at full rank, let C be rC × rX and A be P × rA. For determining p-values, Fi (i ∈ {...

Dynamic force spectroscopy has become indispensable for the exploration of the mechanical properties of proteins. In force-ramp experiments, performed by utilizing a time-dependent pulling force, the peak forces for unfolding transitions in a multimeric protein (D)(N) are used to map the free energy landscape for unfolding for a protein domain D. We show that theoretical modeling of unfolding t...

The study examined the assessement of human factors as determinants of road traffic accidents among commercial vehicle drivers in Gbonyin Local Government Area of Ekiti State. 210 structured questionnaires were administered to commercial vehicle drivers at motor parks in selected towns in the study area. The descriptive statistics of frequency counts and simple percentage was used to analyze de...