conclusions capillaria hepatica should be considered in differential diagnoses in any child with fever, hepatomegaly, eosinophilia and hyperglobulinemia. case presentation the current paper reports a case of capillaria hepatica infection in a four-year-old boy which presented with fever, hepatomegaly, peripheral eosinophilia, and noticeable weight loss. the diagnosis was made on the histologica...

objective(s): fascioliasis is a zoonotic parasitic disease caused by liver fluke species of fasciola hepatica and fasciola gigantica. differentiation of these two species, based on their morphological characteristics, is difficult. the current study aimed to use pcr-rflp assay to distinguish between f. hepatica and f. gigantica , based on profiles of rflp, produced by effect of endonucleases on...

background: fascioliasis is a chronic hepatic disease and may be resulted from mechani­cal/molecular parasite adhesion to host liver tissue. the aim of this study was to detect surface car­bohydrate and lectin, carbohydrate-binding protein isolation that might be responsible of this molecular binding. methods: the present experimental work was conducted in the department of medical parasitol­og...

In this paper, a serological assay for the detection of antibodies to Capillaria hepatica, a zoonotic parasite, is described. In the past, the only way of detecting Capillaria hepatica was to perform a liver biopsy. The indirect immunofluorescence (IIF) assay, based on liver sections of naturally infected mice and human serum samples, is suitable for detecting early stages of human infections a...

Understanding genetic structure and status of genetic variation of Fasciola hepatica isolates from different hosts, has important implications on epidemiology and effective control of fasciolosis. Random amplified polymorphic DNA (RAPD-PCR) was used to study the genetic variation of F. hepatica in sheep and cattle. DNA was extracted from adult helminthes removed from livers of each infected ani...

Background: Cysteine proteases of the liver fluke, Fasciola hepatica, participate in catabolism of proteins, migration of the fluke through host tissues and combat host immune system. Objectives: In this study, we evaluated proteolytic activity of F. hepatica recombinant cathepsin L1 (rCL1) against gelatin and collagen as common substrat...

A case of ectopic fascioliasis due to migration of an immature Fasciola hepatica fluke is described in a 23 year old woman from western Iran.

human fascioliasis due to unknown species and animal fascioliasis caused by both or one of fasciola spp. are commonly seen in iran. to compare electrophoretic patterns of somatic and excretory-secretory antigens of f. hepatica and f. gigantica  by sodium dodecyl sulphate polyacrylamide gel electrophoresis (sds-page), the adult flukes were collected from infected slaughtered bovine livers. e/s a...