The purpose of this study was to identify and characterize clusters in a heterogeneous breast cancer computer-aided diagnosis database. Identification of subgroups within the database could help elucidate clinical trends and facilitate future model building. A self-organizing map (SOM) was used to identify clusters in a large (2258 cases), heterogeneous computer-aided diagnosis database based o...

Connexin(Cx)43 is the major gap junction protein present in osteoblasts. We have shown that overexpression of Cx45 in osteoblasts expressing endogenous Cx43 leads to decreased cell-cell communication (Koval, M., S.T. Geist, E.M. Westphale, A.E. Kemendy, R. Civitelli, E.C. Beyer, and T.H. Steinberg. 1995. J. Cell Biol. 130:987-995) and transcriptional downregulation of several osteoblastic diffe...

LetK be a nonempty closed convex subset of a real Hilbert space H , and assume that Ti : K → H, i = 1, 2...N be a finite family of ki-strictly pseudo-contractive mappings for some 0 ≤ ki ≤ 1 such that ⋂N i=1 F (Ti) = {x ∈ K : x = Tix, i = 1, 2...N} = ∅. For the following iterative algorithm in K, for x1, x ′ 1 ∈ K and u ∈ K, { yn = PK [kxn + (1− k)Σi=1λiTixn] xn+1 = βnxn + (1− βn)yn and { y′ n ...

Due to the widespread use of screening endoscopy, the number of endoscopic procedures has increased considerably over the last decade. In recent years, advanced interventional endoscopic procedures, including endoscopic retrograde cholangiopancreatography, endoscopic ultrasonography, endoscopic submucosal dissection, and peroral endoscopic myotomy, has widely been adopted. Along with the develo...

metabolic diseases in china have been on the rise in recent decades, partially due to reduced cereal consumption and excessive intake of low glycemic index (gi) foods such as meat and oil. although the relationship between dietary glycemic load (gl) and various metabolic diseases has been extensively studied worldwide, it is unclear whether dietary gl is related to blood lipid levels and dyslip...

1. Gupta NM, Kaman L. Personal management of 57 consecutive patients with esophageal perforation. Am J Surg. 2004;187:58– 63. 2. Vallböhmer D, Hölscher AH, Hölscher M, Bludau M, Gutschow C, Stippel D, et al. Options in the management of esophageal perforation: analysis over a 12-year period. Dis Esophagus. 2010;23:185–90. 3. Cameron JL, Kieffer RF, Hendrix TR, Mehigan DG, Baker RR. Selective no...