نتایج جستجو برای: fluconazole
تعداد نتایج: 4748 فیلتر نتایج به سال:
The ability of a fluconazole-containing agar screen assay to accurately detect isolates of Candida glabrata resistant to the azole antifungal agent fluconazole was evaluated on a collection of 100 clinical isolates of this organism. Results were correlated with the MIC of fluconazole for these isolates and compared with the results of a previously published disk diffusion-based fluconazole resi...
background and purpose: candida species constitute an important group of opportunistic fungi, which cause various clinical diseases. considering the resistance of some candida species to conventional antifungal agents, treatment of such cases may be challenging and complicated. the purpose of this study was to evaluate and compare the antifungal activities of euphorbia macroclada latex and fluc...
IMPORTANCE Invasive candidiasis in premature infants causes death and neurodevelopmental impairment. Fluconazole prophylaxis reduces candidiasis, but its effect on mortality and the safety of fluconazole are unknown. OBJECTIVE To evaluate the efficacy and safety of fluconazole in preventing death or invasive candidiasis in extremely low-birth-weight infants. DESIGN, SETTING, AND PATIENTS Th...
OBJECTIVE To demonstrate whether fluconazole reduces multiple organ failure and mortality in early septic shock (<24 hrs). DESIGN A prospective randomized double-blind study. SETTING A medical and surgical adult intensive care unit in a tertiary referral center. PATIENTS Values were obtained from 71 general adult intensive care unit patients. INTERVENTIONS During a 2.5-yr period, Decemb...
BACKGROUND Anidulafungin, a new echinocandin, has potent activity against candida species. We compared anidulafungin with fluconazole in a randomized, double-blind, noninferiority trial of treatment for invasive candidiasis. METHODS Adults with invasive candidiasis were randomly assigned to receive either intravenous anidulafungin or intravenous fluconazole. All patients could receive oral fl...
BACKGROUND Disseminated fungal infections are common presenting opportunistic infections among AIDS patients in developing countries. Primary prophylaxis with itraconazole has been shown to be effective in northern Thailand. This study aimed to compare the efficacy of fluconazole vs itraconazole as primary prophylaxis for fungal infections in HIV-infected patients. METHODS A retrospective coh...
Azole antifungal agents, and especially fluconazole, have been used widely to treat oropharyngeal candidiasis in patients with AIDS. An increasing number of cases of clinical resistance against fluconazole, often correlating with in vitro resistance, have been reported. To investigate the mechanisms of resistance toward azole antifungal agents at the molecular level in clinical C. albicans isol...
Background and purpose: Malassezia, a yeast-like fungus found in normal skin flora is known to be associated with various skin diseases, along with systemic infections. Our aim was to determine the in -vitro susceptibility of Malassezia spp. to ketoconazole and fluconazole. Materials and methods: In this study, we identified 99 Malassezia isolates from patients with pityriasis vesicular by...
Microbiota studies are an increasingly important issue today. In the literature, there limited on antifungal resistance and biofilm formation capacity of yeasts isolated from mouths young individuals. For this reason, our study was carried out with 133 yeast isolates 17 individuals between ages 18-25 in 2018-2020. When biofilm-forming capacities were examined, it determined that 99.25% producer...
The effects of amphotericin B and fluconazole on the extracellular and intracellular growth of Candida albicans were studied. With respect to the extracellular growth of C. albicans, antifungal activity was measured in terms of MICs and minimal fungicidal concentrations as well as by determination of the concentration that effectively killed (greater than 99.9%) C. albicans in the absence or pr...
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