Hundreds of distinct epilepsy-causing genes have been identified.1 The vitamin B6-dependent epilepsies are a heterogeneous group genetic disorders due to incomplete formation, transport, or inactivation pyridoxal 5′-phosphate (PLP).2 ALDH7A1 , PNPO ALPL ALDH4A1 and more recently PLPBP implicated.3 Characteristic presentation includes neonatal onset encephalopathy seizures refractory first-line ...

The nasal passages mainly adjust the temperature and humidity of inhaled air to reach the alveolar condition required in the lungs. By contrast to most other non-human primates, macaque monkeys are distributed widely among tropical, temperate and subarctic regions, and thus some species need to condition the inhaled air in cool and dry ambient atmospheric areas. The internal nasal anatomy is be...

In this article, the electro-osmotic flow of Oldroyd-B fluid in a circular micro-channel with slip boundary condition is considered. The corresponding fractional system is represented by using a newly defined time-fractional Caputo-Fabrizio derivative without singular kernel. Closed form solutions for the velocity field are acquired by means of Laplace and finite Hankel transforms. Additionally...

This study presents the computational analysis of three dimensional Casson and Carreau nanofluid flow concerning the convective conditions. To do so, the flow equations are modified to nonlinear system of ODEs after using appropriate self-similarity functions. The solution for the modified system is evaluated by numerical techniques. The results show the impacts of involving variables on flow c...

Electrostatically actuated microbeams have been studied by many researchers in the last few years. The aim of this study is to present an improved numerical analysis of the dynamic instability of a cantilever microbeam immersed in an incompressible viscous fluid. The finite element method is used for solving the vibrational equation of the microbeam and the potential functions of the fluids in ...

Multiple kernel learning (MKL) optimally combines the multiple channels of each sample to improve classification performance. However, existing MKL algorithms cannot effectively handle the situation where some channels are missing, which is common in practical applications. This paper proposes an absent MKL (AMKL) algorithm to address this issue. Different from existing approaches where missing...

The example of the ‘‘absent-minded driver’’ was introduced by Piccione and Rubinstein in the context of games and decision problems with imperfect recall. They claim that a ‘‘paradox’’ or ‘‘inconsistency’’ arises when the decision reached at the ‘‘planning stage’’ is compared with that at the ‘‘action stage.’’ Though the example is provocative and worth having, their analysis is questionable. A...

Two experiments were conducted to explore Gillam and Borsting's (1988, Perception 17 603-608) report that uncorrelated monocular texture facilitates stereopsis by shortening the latency to see depth in random-dot stereograms. Experiment 1 used stereograms similar, in pattern but not disparity, to Gillam and Borsting's with monocular texture present or absent. A third condition, where monocular ...

Absent or abnormal laxity of splenic ligaments may give rise to a rare condition called wandering spleen. This can be difficult diagnose due its non-specific symptoms and clinical findings which are often missed the patient presents late with life-threatening complication.