PLGA microspheres are widely studied for controlled release drug delivery applications, and many models have been proposed to describe PLGA degradation and erosion and drug release from the bulk polymer. Autocatalysis is known to have a complex role in the dynamics of PLGA erosion and drug transport and can lead to size-dependent heterogeneities in otherwise uniformly bulk-eroding polymer micro...

Biochemical mechanisms of production of redox intermediates of redox-cycling drugs include: photochemical events, either photoionization process or electron transfer from photoexcited states; electron exchange of reduced form of a drug with the oxy state of oxygen-binding hemoproteins; oxidation by catalytic metal centers (oxidases, peroxidases, oxygenases) of the reduced forms of drugs; or ele...

The objective of the present chapter is to analyze the radiation and mass transfer effects on an unsteady two-dimensional laminar mixed convective boundary layer flow of a viscous, incompressible, electrically conducting chemically reacting fluid, along a vertical moving semi-infinite permeable plate with suction, embedded in a uniform porous medium, in the presence of transverse magnetic field...

We obtain the Bethe Ansatz equations for the broken ZN -symmetric model by constructing a functional relation of the transfer matrix of L-operators. This model is an elliptic off-critical extension of the Fateev-Zamolodchikov model. We calculate the free energy of this model on the basis of the string hypothesis.

In the present study, the effect of various nanofluids on mass transfer coefficients in an irregular packed liquid-liquid extraction column was investigated. The chemical system of toluene–acetic acid–water was used. 10 nm SiO2, TiO2 and ZrO2 nanoparticles with various concentrations were dispersed in toluene-acid acetic to provide nanofluids. The influence of concentration and hydrophobicity/h...

In order to improve the efficiency and rate of heat transfer in heat exchangers, various techniques such as increasing the heat transfer coefficient are proposed. This study is devoted to the investigation of heat transfer coefficient variations due to the addition of CuO, TiO2 and CuO/TiO2 nanoparticles into a shell and tube heat exchanger. CuO/TiO2 nanocomposite was synthesized using mechanic...

In this research, the thermodynamics and mass transfer of CO2 absorption has been studied in a mixture of MDEA-MEA amines. A relation is presented for mass transfer flux in the reactive-absorption process. For this purpose, the effective parameters on the mass transfer flux were investigated in both liquid and gas phases. Then, using dimensional analysis with the Pi-Buckingham theorem, the effe...

Membrane contactor using amine based absorbents is an efficient technology for CO2 separation from gaseous mixtures. A novel porous polysulfone (PSF) flat membrane was prepared via non-solvent phase inversion method. The PSF membrane was modified by adding polyvinyl pyrrolidone (PVP) to the dope solution. The fabricated membrane was used in the serpentine flow field contactor module for CO2 abs...

A theoretical model is developed to investigate the influence of hemoglobin-based oxygen carriers (HBOCs) on oxygen transport in capillary-size vessels. A discrete cell model is presented with red blood cells (RBCs) represented in their realistic parachute shape flowing in a single file through a capillary. The model includes the free and Hb-facilitated transport of O2 and Hb-O2 kinetics in the...

The purpose of this study was to determine whether the free cholesterol of hypercholesterolemic low density lipoprotein from cholesterol-fed nonhuman primates has a greater potential for surface transfer to cell membranes than does the free cholesterol of normal low density lipoprotein. The low density lipoproteins were isolated from normal and hypercholesterolemic rhesus and cynomolgus monkeys...