The radioprotective effect of indralin in rhesus monkeys was examined over 60 d following gamma irradiation. Male and female rhesus macaques (Macaca mulatta) 2-3-years-old and weighing 2.1-3.5 kg were used. Animals were exposed to total-body gamma irradiation from (60)Co at a dose of 6.8 Gy (lethal dose, 100% lethality over 30 days). Indralin (40-120 mg kg(-1)) was administered intramuscularly ...

Analysis of gamma-H2AX foci in blood lymphocytes is a promising approach for rapid dose estimation to support patient triage after a radiation accident but has one major drawback: the rapid decline of foci levels post-exposure cause major uncertainties in situations where the exact timing between exposure and blood sampling is unknown. To address this issue, radiation-induced apoptosis (RIA) in...

the radiophotoluminescence property of some materials makes it possible to use them for dosimetry purposes. the silver activated metaphoshate glass 1 as an rpl dosimeter when exposed to x. or y radiations , forms fluorescent centers with long lived states ( metastate ). the silver ions (ag+) in unirradiated state produces vacancies when energy is supplied by irradiation the release of electrons...

background: radio-adaptive response and bystander effects are known phenomena occurring in cells following exposure to ionizing radiation (ir). in this study we examined possible radio-adaptation of lymphocytes following bystander effects induced by cho-k1 cells. materials and methods: whole blood and cho-k1 cells were cultured in rpmi-1640 complete medium. cells were separately irradiated with...

Introduction: Neutrons have many applications in various fields, such as medicine. The important application of neutron in medical science is in Boron Neutron Capture Therapy (BNCT). Because of this, determination of neutron dose and flux is critical for the health maintaining of workers and patients exposed to this beam. The neutron radioisotope sources produce gamma rays in ...

Background: Radioprotective effect of famotidine was previously shown on radiation induced micronuclei and chromosomal aberrations in human peripheral lymphocytes and mouse bone marrow cells however, its radioprotective property has never been studied in mouse spermatogenesis. It was also shown that vitamin C as an antioxidant also exert its radioprotective effect on many biological s...

Introduction: This Study has was  carried out to measure and detect the natural occurred radionuclide content including 226Ra, 232Th and 40K in the  Nile River sediments at various locations in Upper Egypt, from Aswan to El-Minya. Additionally, we determine the absorbed dose rate, the annual effective dose equivalent, and excess lifetime cancer risk also has been calculated. Material and Metho...

Introduction The leukemogenic effect of ionising radiation has been well established for high-dose exposure. In contrast, the risk associated with natural radiation exposure still needs to be documented. Ecological studies have suggested a positive association between indoor radon concentration and childhood leukaemia, which has not been confirmed by case-control studies. The studies that inves...

The commercial used the 555 single timer and 741 operational amplifiers (op-amp) were investigated under gamma-ray radiation of Co-60 source. maximum total doses 2 kGy 4 to irradiate. abnormal behavior in circuit frequency was observed, which decreased from 202 195 Hz at 744 Gy radiations. In op-amp circuit, output signal dropped 1.28 1.25 same dose. loss amplitude calculated about 2.3 % when d...

Background: Interactions of free radicals from ionizing radiation with DNA can induce DNA damage and lead to mutagenesis and carsinogenesis. With respect to radiation damage to human, it is important to protect humans from side effects induced by ionizing radiation.In the present study, the effects of arbutin were investigated by using the micronucleus test for anti-clastogenic activity, to cal...