نتایج جستجو برای: gene disruption

تعداد نتایج: 1185457  

Journal: :Bioinformatics 2002
Johan Rung Thomas Schlitt Alvis Brazma K. Freivalds Jaak Vilo

MOTIVATION Microarray experiments comparing expression levels of all genes in yeast for hundreds of mutants allow us to examine properties of gene regulatory networks on a genomic scale. We can investigate questions such as network modularity, connectivity, and look for genes with particular roles in the network structure. RESULTS We have built genome-wide disruption networks for yeast, using...

Journal: :Endocrinology 2010
Subhankar Das Edward Au Stephen T Krazit Kailash N Pandey

Binding of atrial and brain natriuretic peptides to guanylyl cyclase-A/natriuretic peptide receptor-A produces second messenger cGMP, which plays an important role in maintaining renal and cardiovascular homeostasis. Mice carrying a targeted disruption of the Npr1 gene coding for guanylyl cyclase-A/natriuretic peptide receptor-A exhibit changes that are similar to those that occur in untreated ...

Journal: :The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 2009

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