نتایج جستجو برای: h4
تعداد نتایج: 5638 فیلتر نتایج به سال:
BACKGROUND Novel vaccine strategies are required to provide protective immunity in tuberculosis (TB) and prevent development of active disease. We investigated the safety and immunogenicity of a novel TB vaccine candidate, H4:IC31 (AERAS-404) that is composed of a fusion protein of M. tuberculosis antigens Ag85B and TB10.4 combined with an IC31® adjuvant. METHODS BCG-vaccinated healthy subjec...
An in vitro transcription system has been developed from 0.3M NaCl extracts of nuclei of Drosophila embryos. Optimal transcription in the Drosophila embryo extract (DEX) was at 5mM MgCl2, 70mM KCl, 25 degrees C and with promoter concentrations of 0,75-1.0 pmol/assay. In vitro transcription from the Adenovirus-2 major late and the Drosophila histone gene promoters was studied in particular. S1-n...
Dosage compensation balances gene expression levels between the sex chromosomes and autosomes and sex-chromosome-linked gene expression levels between the sexes. Different dosage compensation strategies evolved in different lineages, but all involve changes in chromatin. This paper discusses our current understanding of how modifications of the histone H4 tail, particularly changes in levels of...
An increasing rate of infections with Shiga toxin/verotoxin-producing Escherichia coli (STEC/VTEC) O104:H4 has been observed in Germany since May 2011, with unusually high numbers of patients suffering from haemolytic uraemic syndrome (HUS). We report a STEC/VTEC O104:H4 case without HUS, presenting with colonic ischaemia demanding surgery. This atypical clinical presentation of STEC O104:H4 in...
<h4>Penelitian ini dilakukan untuk mendeskripsikan bahasa Minangkabau yang mengalami penghilangan (<em>omission</em>) serta perubahannya. Penelitian menggunakan metode deskriptif kualitatif. Data dalam penelitian berupa tuturan kata-kata Minangkabau. Sumber data adalah seorang penutur berasal menguasai di Cipadu. dikumpulkan teknik pancing, wawancara, rekam, simak dan catat. B...
از واکنش سه جزیی آمونیوم استات با 3-فرمیل کرومن و کتوآزیریدینهای از پیش تهیه شده در اتانول مطلق به عنوان حلال، برخی از مشتقات هتروسیکلی 1،3-دیآزابیسیکلو[3.1.0]هگز-3-ان-2-یل]-H4-کرومن-4-اونها برای اولین بار سنتز شدند. کتوآزیریدین ها از واکنش چالکون ها با محلول برم در کلروفرم و سپس واکنش ترکیبات کتو دی برمید حاصل با محلول اتانولی آمونیاک سنتز شدند. ساختار ترکیبات فتوکرومیک سنتز شده...
OBJECTIVE Autoimmune diabetes is a T cell-mediated disease in which insulin-producing β-cells are destroyed. Autoreactive T cells play a central role in mediating β-cell destruction. B7-H4 is a negative cosignaling molecule that downregulates T-cell responses. In this study, we aim to determine the role of B7-H4 on regulation of β-cell-specific autoimmune responses. RESEARCH DESIGN AND METHOD...
Purpose: Cancers have developed a number of strategies to escape immune responses including the differential expression of costimulatory molecules of the B7 family. B7-H3 and B7-H4 have recently been described in different tumor entities but the relevance for melanoma has not yet been studied so far. Experimental Design: Using immunohistochemistry, B7-H3 and B7-H4 expression was studied on 29 m...
This study aimed to identify N-acylhomoserine lactone (AHL) produced by Hafnia alvei H4, which was isolated from spoiled instant sea cucumber, and to investigate the effect of AHLs on biofilm formation. Two biosensor strains, Chromobacterium violaceum CV026 and Agrobacterium tumefaciens KYC55, were used to detect the quorum sensing (QS) activity of H. alvei H4 and to confirm the existence of AH...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید