In humans, spironolactone and mespirenone are well known antimineralocorticoids without C-11b substituents. These compounds display antagonist properties by acting through the human androgen receptor (hAR). In contrast, we demonstrate here that synthetic mineralocorticoid antagonists bearing hydrophobic C-11b substituents and C-17g-lactone are potent hAR agonists in vitro. The three-dimensional...

English) A global mapping of early stage medical technology companies active in the neurology field has been implemented. The companies have emerging products and have undergone an evaluation by clinicians concerning the ability to provide clinical value for Swedish health care. The evaluation process has been executed by discussion with neurologists and neurosurgeons in combination with a lite...

The domestication is the process where animals have adapted to human conditions. A prerequisite for domestication is tame behaviour towards humans and subsequently, selection for other desirable traits took place which led to changes in several behavioural and physiological parameters. The domestication of chickens (Gallus gallus) was initiated around 8000 years ago, and today we see clear phen...

Ad 3. Studienævnsrapport. Rapporten viser, at Dansk har pæne tal bortset fra frafaldstallet. LKØ har ringet til de studerende for at finde forklaringen på frafaldet. Løsningen kunne være en form for adgangsbegrænsning og slut med at optage studerende efter adgangsfristen. Det er også nødvendigt med en samtale med de frafaldstruede studerende. Fakultetet vil have kommentarer til frafaldet. GA fo...

Det här är en undersökning som knyter an till en tidigare publicerad artikel om nitratfri luttring av ett soda-kalk-glas[1]. Det är ur miljösynpunkt bättre att använda antimonat som luttringsmedel efter som utsläppen av NOx-gaser blir betydligt mindre då inget nitrat tillsätts. Antimonat ger i soda-kalk-glaset lika god luttrande effekt som nitrat och antimonoxid. I den här artikeln har studien ...