Developing gene therapy strategies may allow contemporary medicine to reassess its management of solid malignancies. We have demonstrated previously that the wild-type p53 adenovirus (Ad5CMV-p53) suppressed the growth of established tumors of the head and neck. In this paper we develop a microscopic residual model which mimics the postsurgical environment of head and neck cancer patients with a...

Computerized tomography (CT) and magnetic resonance imaging (MRI), positron emission tomography (PET) and the hybrid modality of PET/CT are sensitive and reliable tools for detection and staging of head and neck cancers. This article describes the role of PET/CT in initial staging of head and neck squamous cell carcinoma, the utility of CT/MR perfusion imaging in qualitative analysis of tumor t...

The dynamic analysis of the biomechanical model of the head load impact using the Differential Transform Method is presented in this paper. In many parts of the world, the problem of traumatic brain injuries (TBI) has led to neurodegenerative dementing disorders and diseases as a result of head load impact from sporting activities, accidents involving the head, etc. have serious effects on huma...

INTRODUCTION Synovial sarcoma (SS) is uncommon high grade soft tissue sarcoma, accounting for less than 10% of all head and neck sarcomas. Also, about 10% of SS occur within the Head & Neck. In the pediatric population, SS is an extremely rare head & neck malignancy. PRESENTATION OF CASE We present a case of sixteen years old boy diagnosed with SS situated of the hypopharynx treated by surgic...

Rhabdomyosarcoma (RMS) is the most common childhood malignancy of the head and neck. The Intergroup Rhabdomyosarcoma Study now divides head and neck RMS into three categories by site of origin: orbital, parameningeal (middle ear, paranasal sinuses, and nasopharynx), and all other head and neck sites. CT is clinically applicable in the diagnosis of RMS of the head and neck, in treatment planning...

In the past decade, dynamic contrast-enhanced MR imaging has had an increasing role in assessing the microvascular characteristics of various tumors, including head and neck cancer. Dynamic contrast-enhanced MR imaging allows noninvasive assessment of permeability and blood flow, both important features of tumor hypoxia, which is a marker for treatment resistance for head and neck cancer. Dynam...

objective(s): in clinical practice, approximately 10-25% of post-surgical differentiated thyroid carcinoma (dtc) patients with high serum thyroglobulin (tg) and negative 131i whole-body scan (wbs) have poor prognosis due to recurrent or metastatic lesions after radioactive iodine treatment. the purpose of this study was to evaluate the value of 18f-fdg pet/ct scan in dtc patients with high seru...