Background: SEN virus (SENV) is the latest virus proposed as a cause of unknown hepatitis cases. Among nine detected genotypes of the virus, genotypes D and H are more frequent in hepatitis cases of unknown origin. The aim of this study was to determine the frequency of SENV-D and SENV-H genotypes in the sera of healthy individuals and hepatitis B and C patients. Methods: Totally, 200 serum sam...

Background and Objectives: Accurate detection of type and severity of Hepatitis is crucial for effective treatment of the disease. While several computational algorithms for detection of Hepatitis have been proposed to date, their limited performance leaves room for further improvement. This paper proposes a novel computational method for the diagnosis of Hepatitis B using pattern detection tec...

Beginning with this issue, a new table will appear monthly in the MMWR:"Table V. Potential Years of Life Lost, Deaths, and Death Rates, by Cause of Death, and Estimated Number of Physician Contacts, by Principal Diagnosis" (see page 557). By displaying a variety of measures that gauge the importance and relative magnitude of certain public health issues, this table will call attention to those ...

BACKGROUND Patient's satisfaction with monitoring frequency is of interest when implementing six-monthly monitoring for well-controlled type 2 diabetes patients. Here we want to determine the satisfaction of well-controlled type 2 diabetes patients with either three-monthly or six-monthly diabetes monitoring and their future preference. METHODS Survey among 2215 well-controlled type 2 diabete...

OBJECTIVE To treat decompensated hepatitis C patient with interferon, ribavirin and amantidine to ascertain the sustained viral response. STUDY DESIGN Descriptive study. PLACE AND DURATION OF STUDY Shifa International Hospital, Islamabad, from January 2007 to January 2012. METHODOLOGY HCV PCR patients with decompensated hepatitis C, who had developed a complication like ascites, encephalo...

I read with interest the article by Kashani et al, on the use of hydroxyurea (HU) in the treatment of chronic hepatitis B published in Hepatitis Monthly (1). In their article, the authors performed a limited pilot study and concluded that HU effectively blocks HBV replication. Favorable dosing schedule, safety profile, and cost make HU a very attractive adjunct to the therapeutic armamentarium ...

OBJECTIVE To determine the response of one-year interferon-alpha therapy in hepatitis delta virus (HDV) infection in children and young adults at a tertiary care hospital, Karachi, Pakistan. STUDY DESIGN An observational study. PLACE AND DURATION OF STUDY Sarwar Zuberi Liver Centre (SZLC), Medical Unit IV, Civil Hospital, Karachi/Dow University of Health Sciences (DUHS), from June 2009 to J...

AIMS To determine the effects of 1) a condom distribution program and 2) a condom distribution program combined with opt-out sexually transmitted infection (STI) screening on the transmission and prevalence of STIs in a prison system. METHODS Using data from an implementation evaluation of a state-wide prison condom program and parameter estimates from available literature, a deterministic mo...

Background and Aims: Viral hepatitis is a global health problem with a high mortality rate. Recently, a new Flavi-like virus, provisionally named hepatitis G virus (HGV), has been described. HGV does not induce an immune response that is consistently detectable by using recombinant proteins from prokaryotic expression, therefore studies have been conducted by using polymerase chain reaction (...