نتایج جستجو برای: high glucose toxicity

تعداد نتایج: 2294423  

Journal: :pharmaceutical and biomedical research 0
احسان زمانی ehsan zamani department of toxicology and pharmacology, faculty of pharmacy, mazandaran university of medical sciences, 18th kilometers of darya road, sari, iran.مازندران، کیلومتر 18 جاده دریا، دانشگاه علوم پزشکی مازندران، دانشکده داروسازی، گروه سم شناسی و فارماکولوژی محمد شکرزاده mohammad shokrzadeh department of toxicology and pharmacology, faculty of pharmacy, mazandaran university of medical sciences, 18th kilometers of darya road, sari, iran.مازندران، کیلومتر 18 جاده دریا، دانشگاه علوم پزشکی مازندران، دانشکده داروسازی، گروه سم شناسی و فارماکولوژی مرجان فلاح marjan fallah department of toxicology and pharmacology, faculty of pharmacy, mazandaran university of medical sciences, 18th kilometers of darya road, sari, iran.مازندران، کیلومتر 18 جاده دریا، دانشگاه علوم پزشکی مازندران، دانشکده داروسازی، گروه سم شناسی و فارماکولوژی فاطمه شکی fatemeh shaki department of toxicology and pharmacology, faculty of pharmacy, mazandaran university of medical sciences, 18th kilometers of darya road, sari, iran.مازندران، کیلومتر 18 جاده دریا، دانشگاه علوم پزشکی مازندران، دانشکده داروسازی، گروه سم شناسی و فارماکولوژی

acrylamide (aa) is an important industrial chemical agent that is mainly used in the production of polymers and copolymers. recently it has been attention because of its production in the diet at high-temperature (>120 ºc) processes such as cooking, frying, toasting, roasting or baking of high carbohydrate foods. according to high exposure to acrylamide, recognition of its toxic effect is neces...

Journal: :European review for medical and pharmacological sciences 2016
X-S Hu D-L Cheng K-J Li L-B Wang X Yang S Sun Y-P Wang S-H Li Z-F Lei Z-Y Zhang

OBJECTIVE The root of Helicteres angustifolia L. (Sterculiaceae) has been used as tea to treat diabetics effectively by local people in Laos. However, no scientific evidence is available for this ethnomedicinal usage. This study was undertaken to explore the hypoglycemic effect of aqueous extract from Helicteres angustifolia root. PATIENTS AND METHODS The effect of aqueous extract from Helict...

Chhanda Mallick, Debidas Ghosh, Rajkumar Maiti,

Herbal medicine development against the non-communicable disease like diabetes is one of the thrust area of research in the field of global medicine. Here we have studied the separate and composite methanolic extract of seed of Eugenia jambolana and root of Musa paradisiaca for the management of streptozotocin-induced diabetes mellitus. We have measured the fasting blood glucose level and glyco...

Journal: :British medical journal 1987
J J Bending C S Ogg G C Viberti

A young woman given a renal allograft for polycystic kidney disease developed insulin dependent diabetes mellitus 25 days after transplantation. There was no family history of diabetes, plasma glucose concentrations had been normal at presentation and on five subsequent occasions, and at no time were islet cell antibodies detectable. Plasma C peptide concentrations, however, were greatly suppre...

Journal: :Revista de biologia tropical 2006
Mildred García-González Teresita Coto Morales Rafael Ocampo Liliana Pazos

We tested the effects of the aqueous extract of Petiveria alliacea leaves on acute and sub-chronic toxicity, hematocrit and blood glucose level and intestinal motility of male albino NGP mice of 20 to 25 g mean weight. Treatments were in all cases doses of 1,000 and 2,000 mg/kg animal weight and a control treatment with 0.5 ml distilled water, using 10 animals per treatment and administered ora...

Hamid Reza Sadeghnia, Mozhgan Asghari, Seyed Hadi Mousavi, Zahra Tayarani-Najaran,

Introduction: The Serum/Glucose deprivation -induced cell death in cultured PC12 cells represents a useful in vitro model for the study of brain ischemia and neurodegenerative disorders. Nigella sativa L. has been known as a source of antioxidants. To elucidate the neuroprotective actions of N. sativa extract in vitro, we studied the effect of N. sativa extract on cultured PC12 cells under s...

2014
Ling Wang Yu Wang Yong Liang Jia Li Yuchen Liu Jie Zhang Aiqian Zhang Jianjie Fu Guibin Jiang

Male BALB/c mice fed with either a regular or high fat diet were exposed to 0, 5 or 20 mg/kg perfluorooctane sulfonate (PFOS) for 14 days. Increased body weight, serum glucose, cholesterol and lipoprotein levels were observed in mice given a high fat diet. However, all PFOS-treated mice got reduced levels of serum lipid and lipoprotein. Decreasing liver glycogen content was also observed, accom...

Journal: :Metabolism: clinical and experimental 1998
R R Shankar J S Zhu A D Baron

Sustained hyperglycemia can cause peripheral insulin resistance and pancreatic beta-cell dysfunction and has been termed glucose toxicity or glucose-induced desensitization. Glucosamine, a product of glucose flux through the hexosamine biosynthetic pathway (HBP), causes insulin resistance in peripheral tissues and has been shown to cause abnormal glucose-insulin secretion coupling, and thus has...

Journal: :Natural Product Communications 2023

Objective This study aims to evaluate the phytochemical composition, antioxidant, and antihyperglycemic (in vivo, in vitro, silico) activities acute toxicity of Crataegus monogyna Jacq ( C monogyna) aqueous extracts. Methods The analyzed extract through various methods such as screening, high-performance liquid chromatography-ultraviolet (HPLC-UV)-visible analysis. was also tested for antioxida...

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