The technical feasibility of the development of transgenic mosquitoes highly refractory to (rodent) malaria parasites has been demonstrated in the laboratory. Following this proof of principle, genetic control of vectors could have an important role to play in the interruption of transmission of human malarias, if the main developmental and implementation challenges are adequately addressed. Th...

INTRODUCTION Discharge documents are important for transferring information from hospitals to the referring clinician; in the UK and many countries, this is often the patient's general practitioner or family physician. However, patients may or may not receive their discharge letters, and whether patients should routinely receive discharge letters remains unclear. METHODS AND ANALYSIS The revi...

BACKGROUND Comprehensive health technology assessments (HTAs) include thorough reflections on ethical issues associated with health technologies, their use, and value-based decisions in the assessment process. As methods of information retrieval for effectiveness assessments are not applicable to information retrieval on ethical issues, a specific methodological approach is necessary. OBJECTI...

that will impact the creation and operation of neurological disease registries in Canada. This document is not meant to provide legal or ethical advice. In order to ensure that applicable laws and organizational policies are adhered to in an appropriate manner, it is recommended that legal advisors and relevant organizational representatives be consulted. For registries to succeed, it is critic...

New technology brings great benefits, but it can also create new and significant risks. When evaluating those risks in policymaking, there is a tendency to focus on social acceptance. By solely focusing on social acceptance, we could, however, overlook important ethical aspects of technological risk, particularly when we evaluate technologies with transnational and intergenerational risks. I ar...

BACKGROUND In an adaptive clinical trial (ACT), key trial characteristics may be altered during the course of the trial according to predefined rules in response to information that accumulates within the trial itself. In addition to having distinguishing scientific features, adaptive trials also may involve ethical considerations that differ from more traditional randomized trials. Better unde...

The assessment of decision-making capacity is an essential element of competency determinations. As experts in the assessment of human cognitive abilities, neuropsychologists may be the best adjudicators of competency. However, to maximize the contribution of neuropsychology to the courts in the determination of competency, clinicians must be aware of the professional controversies and ethical ...

Summary/Abstract An ethical assessment is a complex, dynamic and comprehensive process that requires both expertise practical knowledge. of genetically modified organism (GMO, including genome edited organisms) must follow accepted transparent methods be based in relevant considerations. In addition, the Ethical guidelines include broad adequate range values, so no groups, stakeholders, agents ...

background: ethical leadership represents the leader's proactive efforts to influence followers' ethical and unethical behavior and follower work attitudes such as perceived organizational support, affective commitment and normal behaviors. the purpose of this research was to test the relationship of ethical leadership and ethical context with affective commitment that mediating the r...

Literature abounds to show that the current anti-corruption strategies have failed to fight corruption because of neglect of ethics in these strategies, despite its importance. The purpose of this paper is to make a contribution to anti-corruption theory by developing a model that clarifies many complex ethical dilemmas around corruption. To develop a conceptual model, the extant literatures on...