Parturition and retention of fetal membranes were induced with PGF2 alpha in 3 primiparous dairy cows. Starting on day 12 post partum (PP) the cows were treated with 500 micrograms i.m. of ACTH-analogue (tetracosactid) every 6 h for 6 times. Changes in plasma concentrations of cortisol, progesterone and 15-ketodihydro-PGF2 alpha were evaluated immediately after treatment. The effects on the res...

We have previously reported that two chemically induced sarcomas of BALB/c mice (MCA-1315 and -1321) contained common transplantation antigens which could be detected by immunization of normal BALB/c mice with irradiated tumor cells of each line. This cross-protection could not be detected in animals surgically cured of these tumor lines and challenged with a high dose of tumor cells, but it wa...

In many mammals, hormonal fluctuations during pregnancy and parturition produce neurochemical events that are necessary for the transition from a non-maternal state to a maternal state that occurs when infants are born. However, the nature of these events is mostly unknown. We investigated whether changes in dopamine (DA) and serotonin (5-HT) activity within the preoptic area (POA) and striatum...