Intramedullary spinal cord tumors (IMSCTs) are lethal diseases to many patients. The lack of adequate animal model has hampered the development of novel treatments. In the current study, a rodent intramedullary glioma model is established to study IMSCT progression. Fischer 344 rats received a intramedullary implantation of RG2 glioma cells. The neurological state of each rat was evaluated on d...

Background and purpose — Literature describing long-term functional outcome osteoarthritis (OA) in adjacent joints after femoral lengthening is rare. We evaluated physical function the presence of radiographic OA 10 patients ? 27 years lengthening.Patients methods conducted a cross-sectional study treated by unilateral lengthening. Follow-up was between 34 years. Physical 30-second sit-to-stand...

INTRODUCTION Distraction osteogenesis is a process for lengthening long bones in which the slow, incremental distraction of fracture callus is used to stimulate and prolong active new bone formation. Distraction osteogenesis is used to treat congenital and acquired limb length inequality, post-traumatic segmental bone loss and deformity, difficult fractures, and chronic medical conditions such ...

Spinal cord cavernous angioma (SCAA) is a rare tumorous condition that can manifest various neurologic symptoms, and most lesions are needed to be removed surgically. However, since the SCAA positioned intramedullary, tumor resection could have modest risk for development of neuronal injury. Intraoperative neurophysiologic monitoring (IONM) has been widely accepted as an effective tool detectin...

Managing complications after attempted hind foot and ankle arthrodesis with intramedullary nail fixation is a challenge. This situation becomes more problematic in the patient with diabetes mellitus and multiple comorbidities. Infection and subsequent osteomyelitis can be a devastating, limb threatening complication associated with these procedures. The surgeon must manage both the infectious p...

The purpose of this study was to determine the incidence and degree of sagittal plane deformity that occurs during limb lengthening of the femur. Twenty-one patients (25 limbs) were identified who underwent femoral lengthening. The limbs were lengthened a mean of 6.1 cm, and mean follow-up was 1.5 years. The immediate postoperative deformity in the sagittal plane was 8.3°; this deformity did no...

Background: This paper describes the establishment of a rat intramedullary spinal cord tumor (IMSCT) model and histopathological characterization of the tumor model. Methods: Fourteen male Wistar rats were randomized into two groups. The rats in group 1 (control group, n = 7) received a 5 μl intramedullary injection of serum physiologic (SF). Those in group 2 (experimental group, n= 7) received...

Lengthening the femur with an external fixator is commonly practised for a wide variety of pathologies. This technical report includes tips derived from observation and experience in a busy limb reconstruction unit. It focuses on the use of a rail fixator, although some of the descriptions are applicable to lengthening by circular fixators.

Abstract Aim The management of limb-length discrepancy secondary to traumatic bone loss poses a unique challenge for surgeons. Ilizarov technique is popular but associated with long external fixator time and many complications. This retrospective study assessed outcomes post-traumatic femoral defects managed by monorail fixation over an intramedullary nail. Method Eight patients were included f...