BACKGROUND Iodide transport defect (ITD) is a dyshormonogenetic congenital hypothyroidism caused by sodium/iodide symporter (NIS) gene mutations. In the lactating mammary gland, iodide is concentrated by NIS, and iodine for thyroid hormone synthesis is thereby supplied to the infant in the breast milk. CASE DESCRIPTION A 34-year-old Japanese woman was diagnosed with ITD caused by a homozygous...

We examined the frequency of iron and iodine deficiencies and associations of iron and iodine deficiencies with common diseases among under-2 children, adolescent girls, and pregnant women of Bangladesh. We assayed the blood hemoglobin concentration in 395 under-2 children, 355 adolescent girls, and 263 pregnant women, the urinary iodine concentration of those adolescent girls and pregnant wome...

OBJECTIVE To describe studies evaluating urinary iodine excretion during pregnancy and lactation in women living in cities with adequate or more than adequate iodine intake. DESIGN Cross-sectional study conducted between 1996 and 1998 in pregnant women and a study of lactating women conducted in 2003. SETTINGS AND SUBJECTS Pregnant women attending prenatal clinics in four cities in the Isla...

We present evidence on the impacts of a large-scale iodine supplementation program in Tanzania individuals' long-term economic outcomes. Exploiting timing and location intervention, we document that utero exposure to increased completed years education income scores adulthood. find no increase total employment, but significant change occupational structure. Cohorts exposed are less likely work ...

UNLABELLED Goitre in the West African sub-region is caused by iodine deficiency and goitrogens in the diet. Supplementary iodine nutrition on a mass scale was started in Ghana in 1996. In areas where iodine deficiency have been corrected the histological pattern of goitre changes and this influences surgical decision making. Data on the histological types of goitre in our institution is lacking...

The iodine status of women of childbearing age in the United States has declined dramatically over the last 25 years (1,2). In fact, using criteria from the World Health Organization, certain subgroups may be classified as iodine deficient (3). Given this dramatic decline in iodine status and the critical role of iodine in fetal neurologic development, in October 2006 the American Thyroid Assoc...