Anaplastic lymphoma kinase (ALK) fusion is a common mechanism underlying pathogenesis of non-small cell lung carcinoma (NSCLC) where these rearrangements represent important diagnostic and therapeutic targets. In this study, we found a new ALK fusion gene, SEC31A-ALK, in lung carcinoma from a 53-year-old Korean man. The conjoined region in the fusion transcript was generated by the fusion of SE...

Recent studies have reported that the majority of prostate cancers express fusion genes in which the 5' region of the androgen-regulated TMPRSS2 gene is fused to an ETS family transcription factor, most commonly the ERG gene. We have characterized in detail the expression of TMPRSS2/ERG fusion mRNAs and correlated the isoforms expressed and expression levels with clinical outcome in cancers fro...

The mixed lineage leukemia (MLL) locus is involved in more than 60 different rearrangements with a remarkably diverse group of fusion partners in approximately 10% of human leukemias. MLL rearrangements include chromosomal translocations, gene internal duplications, chromosome 11q deletions or inversions and MLL gene insertions into other chromosomes, or vice versa. MLL fusion partners can be c...

A useful technique in various applications of remote sensing involves the fusion of panchromatic and multispectral images. Wavelet-based approaches to image fusion generally produce high-quality spectral content in fused images. However, the spatial resolution obtained by most wavelet-based methods is less than that obtained by the intensity-hue-saturation (IHS) method. Recent studies show that...

This paper presents a novel algorithm for obtaining a high spatio-temporal resolution video from two video sequences. These sequences are high resolution with low frame rate and low resolution with high frame rate. To this end, we introduce a dual sensor camera that can capture these sequences with the same field of view simultaneously. The proposed method observes motion information through th...

The final report that summarizes the work performed at University of South Alabama (USA). Four different target tracking algorithms and two data fusion algorithms have been developed for single/multiple target detection and tracking purposes. Each tracking algorithm utilizes various properties of targets and image frames of a given sequence. The data fusion algorithms employ complementary featu...

 In this paper, utilization of clustering algorithms for data fusion in decision level is proposed. The results of automatic isolated word recognition, which are derived from speech spectrograph and Linear Predictive Coding (LPC) analysis, are combined with each other by using fuzzy clustering algorithms, especially fuzzy k-means and fuzzy vector quantization. Experimental results show that the...

The application of high temperature superconductors in long term tokamak fusion reactors is analyzed in this paper. Properties of high temperature superconductors have been well documented that make them ideal for this application. Short-sample BSSCO wires and YBCO tapes approach their single-crystal performance limits. This provides a useful reference frame as well as a starting point of what ...