In the title compound, C(14)H(14)N(2)O(2)S, the dihedral angles between the thio-urea group and the methoxyphenyl and hydroxyphenyl rings are 61.91 (4) and 76.90 (4)°, respectively. The benzene rings are twisted with respect to each other, making a dihedral angle of 71.03 (4)°. The H atoms of the thio-urea NH groups are positioned anti to each other. In the crystal, inter-molecular N-H⋯S, N-H⋯O...

Chinese Beiqishen tea extract was studied in an in vitro test system. Phytochemical screening and trace element analysis as well as the detection of antioxidant properties have been carried out. Total polyphenol content of the tea extract (2 g/250 ml) was 83.2 mg/100 ml, kaemferol content: 1.99 mg/100 ml and quercetin content: 0.75 mg/100 ml. Caffeine was the predominant compound responsible fo...

objective(s): as t-cell immunoglobulin and mucin domain 3 (tim-3) is an immune regulatory molecule; its blocking or stimulating could alter the pattern of immune response towards a desired condition. based on the unique features of nanobodies, we aimed to construct an anti-tim-3 nanobody as an appropriate tool for manipulating immune responses for future therapeutic purposes. materials and meth...