Acute liver failure (ALF) is a medical emergency requiring immediate evaluation for liver transplantation. We describe an unusual case of a patient who presented with ascites, jaundice, and encephalopathy and was found to have ALF due to natural killer (NK)-like T cell leukemia/lymphoma. The key immunophenotype was CD2+, CD3+, CD7+, CD56+. This diagnosis, which was based on findings in the peri...

Introduction: Even the combination of PT and total bilirubin, known for being most reliable predictive conventional markers shows low sensitivity. Therefore we need to find more relevant biomarkers liver failure after resection focused on metabolites. Method: A 20 pigs were divided into 3 groups sham operation (n=6), 70% hepatectomy group (n=7), 90% (n=7). Blood sampling was performed preoperat...

Abstract:Introduction: Patients with acute-on-chronic liver failure(ACLF) have different characteristics from those presented by non-ACLF patients diseases. The degree of ACLF impacts the outcome or without transplantation, divergences in literature, especially regarding post-transplant prognosis. Objectives: To review aspects ACLF, including concepts syndrome adopted various institutions, trea...

PURPOSE OF REVIEW The mortality of acute liver failure remains unacceptably high and liver transplantation is the only effective treatment available to date. This review focuses on new research developments in the field and aims to provide a pragmatic organ-based treatment approach for liver failure patients requiring intensive care support. RECENT FINDINGS The pathophysiological basis for ce...