Male F344 rats were fed a diet containing the peroxisome proliferators 2-[4-(2,2-dichlorocyclopropyl)phenoxy]-2-methylpropionic acid [ciprofibrate (0.025%)] or [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic acid [Wy-14643 (0.1%)] for up to 14 months to determine whether hepatic peroxisome prolifera tion caused by these agents results in the induction of membrane lipid peroxidation in the l...

Microbial resistance towards antibiotic is menacing all over the world and therefore considered to be a global health issue. Their potentialities for adapting new mechanisms threaten our ability treat common infectious diseases. Hence it important explore alternative therapies combat microbial Among them, honeybee products comprise wide variety of dietary/nutritional supplements with range phar...

From the name itself, lipoproteins are made up of complexes of lipids and proteins that primarily work as the transport system for cholesterol, triglycerides and other significant lipids needed by the body. Previously, the study of conditions related to problems in the metabolism of lipoproteins has been exclusive only for researchers focusing on lipids. However, it has been integrated into the...

Lipid droplets are cellular organelles used for lipid storage with a hydrophobic core of neutral lipids enclosed by phospholipid monolayer. Besides presenting as giant single in fat tissue, also widely present multitude small structures hepatocytes, where they play key roles health and disease the liver. In addition to storage, directly involved metabolism, membrane biosynthesis, cell signaling...

“Lipid Accumulation in Hepatic and Extrahepatic Tissues,’’ a research seminar sponsored by the Aspen Bile Acid/Cholesterol Conference, Inc., was held at the Given Institute of the University of Colorado School of Medicine in Aspen, Colorado on August 17-20, 1991. This symposium was planned to bring together investigators who approach the general problem of tissue accumulation of lipids from dif...

Introduction: Silymarine extract is currently prescribed by some physicians for treatment of fatty liver disease. In the present study, the effect of administration of tablet containing silymarine extract on plasma homocysteine (Hcy), folate, vitamin B12 and liver enzymes activity in non-alcoholic steatohepatitis (NASH) was investigated. Materials and Methods: Seventy-four patients (40 female a...

The fatty acid compositions of the intracellular organelles of rat liver, separated by differential centrifuging, and the composition of the rat-liver lipids, have been described by Getz & Bartley (1961) and Getz, Bartley, Stirpe, Notton & Renshaw (1961). This paper describes the lipid composition of the mitochondria, fluffy layer and microsomes isolated from rat liver. A similar study has rece...

The liver plays a primary role in lipid metabolism. Important functions include the synthesis and incorporation of hydrophobic lipids, triacylglycerols and cholesteryl esters into the core of water-miscible particles called lipoproteins and the secretion of these particles into the circulation for transport to distant tissues. In this article, we present a brief overview of one aspect of the as...

The aim of this article is to review health-related aspects of Ramadan fasting in normal individuals and diabetics. During fasting days of Ramadan, glucose homeostasis is maintained by meal taken bepore dawn and by liver glycogen stores. Changes in serum lipids are variable and defend on the quality and quantity of food consumption and changes in weight. Compliant, well controlled type 2 diabet...