materials and methods: in order to achieve this, recombinant plasmid harboring antisense sequences targeting both of pta and acka was assembled, after transfecting to the cells, its effects on the cell growth and acetate accumulation in the minimal media was assessed and compared with the control, the plasmid without antisense cassette, in presence and absence of iptg in escherichia coli bl21 (...

tendency to optimization in last decades has resulted in creating multi-product manufacturing systems. production planning in such systems is difficult, because optimal production volume that is calculated must be consistent with limitation of production system. hence, integration has been proposed to decide about these problems concurrently. main problem in integration is how we can relate pro...

In recent years according to the growing companies andproducts supplied, and competition between them has intensified. Productsand diversity, one of the main concerns of commercial institutions.Therefore, selecting the media to introduce and is important therelationship between customers’ products. Given the multiplicity of mediain promoting and marketing the products, they are the optimalchoic...

The demand for increasing product variety and customization has forced many companies to adopt a make-to-order (MTO) strategy. Traditional push-type MTO suffer from unstable demands, struggling deliver on time, making them consider the utilization of pull systems control production. In present paper, an overview in environments is presented. Moreover, discrete event simulation (DES) model compa...

Original scientific paper Nowadays the production process with as few as possible deadlocks is the most important goal of management in every company. An optimized production process can be reached with well-trained personnel and especially with well-trained schedule planners. In this contribution, a new strategy on how to train production planners for different types of production by using vir...

This paper focuses on formulating capacity-price trade off problem in Yield Management for manufactur-ing industry by drawing motivation from the remarkable success of Yield Management (YM) implementation in airlines. In the current practice, there is no alternative and procedure for the manufacturer, as well as cus-tomers to take advantage of using the unfulfilled capacity in discounted offers...