Objective: This study describes the bone transportation technique for partial bone defect, and shows clinical and radiological results of a series of patients treated by using this method. Material and Methods: Nine patients with partial bone defect were treated (six tibia and three femur). Every patient had infection and nonunion. The initial procedure was to stabilize the bone, followed by a ...

BACKGROUND Osteoarthritis (OA) is a major joint disease in humans and many other animals. Consequently, medical countermeasures for OA have been investigated diligently. This study was designed to examine the regeneration of articular cartilage and subchondral bone using three-dimensional (3D) constructs of adipose tissue-derived mesenchymal stem cells (AT-MSCs). METHODS AT-MSCs were isolated...

Bionic modeling technology of bone defect repair plays a key role in the process of repairing defective bone based on tissue engineering. In this paper, via studying the structure of bone defect repair, new concept of bionic scaffold is put forward and a new method of integrating medical image processing, 3D reconstruction and CAD technology to construct the bionic scaffold of repairing bone de...

Structural bone allografts are widely used in the clinic to treat critical sized bone defects, despite lacking the osteoinductive characteristics of live autografts. To address this, we generated revitalized structural allografts wrapped with mesenchymal stem/progenitor cell (MSC) sheets, which were produced by expanding primary syngenic bone marrow derived cells on temperature-responsive plate...

BACKGROUND Extended Soft tissue defect of leg including middle and distal parts always has been a challenge for many plastic surgeons and also a frustrated problem for patients and families. To introduce the use of the soleus muscle and reverse sural flaps as synchronous surgical treatment alternative of the leg bone exposure with large soft tissue defect, this study was conducted. METHODS T...

Objective- The aim of this study was to evaluate possible beneficial effect of tricalcium phosphate/collagen (TCP/collagene) nanocomposite scaffold on bone healing in rabbits using biochemical assessmentsDesign- Experimental studyAnimals- Twelve healthy male white New Zealand rabbitsProcedures- The rabbits wer...

Fig. 1. Schematic of one stage bone transport procedure (yellow bone, red periosteum). A portion of diaphyseal bone is denuded of periosteum, osteotomized, and transported over an intramedullary nail to the site of the 2.54-cm critical-sized defect, where it is docked to the distal femur. The periosteal sheath is left in situ to surround the new defect site, leading to full infilling of the new...

Fig. 1. Schematic of one-stage bone-transport procedure (yellow – bone, red – periosteum). A portion of diaphyseal bone is denuded of periosteum, osteotomized, and transported over an intramedullary nail to the site of the 2.54-cm critical-sized defect, where it is docked to the distal femur. The periosteal sheath is left in situ to surround the new defect site, leading to full infilling of the...

Restoration of bone defects in the oral cavity is one of the major challenges for dental surgeon. A common example is handling of bone defect after simple tooth extraction for ridge preservation. Often delivering prosthodontic and implant treatments face difficulties during oral rehabilitations in bone defect site. Bone defect site needs to be restored in such a way to support further treatment...