The chemically modified guar gum sulphonic acid (GSA) resin was used for removal and pre-concentration of Zn2+, Cd2+, Fe2+, Pb2+ and Cu2+ ions in aqueous solutions and steel industry effluent from Jodhpur, India. This type of ion exchange resin represents a new class of hybrid ion exchangers with higher stability, reproducibility and selectivity for toxic metal ions. The characterisation of the...

Background: Combination of glycation and oxidation is associated with diabetes mellitus. The aim of this study was to clarify the effect of glycated proteins in presence of transition metal ions on production of reactive oxygen species (ROS) in rat hepatocyte suspension.  Methods: Glycated albumin was prepared by incubation of bovine serum albumin with 100 mM glucose in 0.3 M phosphate buffer a...

Metal chalcogenide semiconductor nanocrystals (NCs) are ideal inorganic materials for solar cells and biomedical labeling. In consideration of the hazard and instability of alkylphosphines, the phosphine-free synthetic route has become one of the most important trends in synthesizing selenide QDs. Here we report a novel phase transfer strategy to prepare phosphine-free chalcogenide precursors. ...

Common adhesives stick to a wide range of materials immediately after they are applied to the surfaces. To prevent indiscriminate sticking, smart adhesive materials that adhere to a specific target surface only under particular conditions are desired. Here we report a polymer hydrogel modified with both β-cyclodextrin (βCD) and 2,2'-bipyridyl (bpy) moieties (βCD-bpy gel) as a functional adhesiv...

The aggregation of β-amyloid peptide (Aβ) into fibrils plays an important role in the pathogenesis of Alzheimer's disease (AD). Metal ions including copper and zinc are closely connected to the precipitation and toxicity of Aβ. In this study, a surface plasmon resonance (SPR) biosensor was constructed to investigate the interactions between Aβ and metal ions. Aβ peptide was immobilized on the S...

A heavy metal ion sensor was constructed by cross-linking melanin onto the gold electrode of quartz crystal microbalance (QCM). A mercury ion sensitivity of 518+/-37 Hz/ppm was observed, a substantial increase in sensitivity compared to previous reports of 10-50 Hz/ppm with the limit of detection at 5 ppb. Detection of other metal ions including Sn(2+), Ge(4+), Li(+), Zn(2+), Cu(2+), Bi(3+), Co...

The discovery of ribozymes nearly 30 years ago triggered a huge interest in the chemistry and biology of RNAs. Much of the recently made progress focusing on metal ions is addressed in MILS 9. This book, written by 28 internationally recognized experts from 8 nations, provides a most up-to-date view and is thus of special relevance for colleagues teaching courses in biological inorganic chemist...

Investigation of nonspecific interactions of metal ions with proteins and studies of biological function of such complexes are of importance (Breslow 1978; Friedberg 1975). Identification of the binding centers of metal ions with proteins and determination of the binding constants are necessary to explain the transfer mechanisms of these ions by proteins. Earlier it has been shown (Lau et al. 1...

Recently there have been a number of reports suggesting the possible importance of metals in ribonucleic acid. Wacker and Vallee (1) have reported the presence of chromium, iron, manganese, nickel, zinc, and other metals in various ribonucleic acid preparations, and have suggested that “metals may bear a functional relationship to protein synthesis and the transmission of genetic information.” ...

Y.V. Li and J.H. Zhang (eds.), Metal Ion in Stroke, Springer Series in Translational Stroke Research, DOI 10.1007/978-1-4419-9663-3_1, © Springer Science+Business Media New York 2012 Abstract Metal ions are used in biology in many ways and are integrated parts of numerous enzymes and proteins. They function as cofactors in cellular and genetic signaling and, therefore, have important roles in b...