BACKGROUND Recent studies have shown that migraine headache is often associated with concomitant gastrointestinal diseases. There is a higher prevalence of headaches in patients with gastrointestinal disorders. These associations between migraine and gastrointestinal disorders suggest a potential link to a bidirectional modulation of gut microbiota and brain function. The underlying working mec...

background: sodium valproate (sv) has been approved for migraine prophylaxis and its intravenous form is used to treat acute migraine attacks. we compared the efficacy and safety of intravenous sv and subcutaneous sumatriptan in managing acute migraine attacks. methods: this double-blind randomized clinical trial divided 90 patients into two groups: one group received 400 mg of intravenous sv a...

OBJECTIVE The aim of this study is to analyze the characteristics of white matter lesions in abnormal manifestations of magnetic resonance imaging (MRI) of patients with migraine, and its relationship with migraine. PATIENTS AND METHODS 38 patients, diagnosed with migraine were continuously selected as the observation group, while during the same period, 30 healthy individuals were selected a...

OBJECTIVE To report the clinical events leading to alteration of an anticoagulation regimen for patients undergoing transcatheter closure of an atrial shunt and how this affected migraine symptoms after the closure procedure. METHOD Audit of a change of anticoagulant regimen. RESULTS In the first few weeks after a closure procedure migraine frequency and severity increased despite treatment...

BACKGROUND Psoriasis and migraine are common conditions with potential overlap of pathophysiological mechanisms. Both these diseases have been associated with increased cardiovascular risk but little is known about their interplay. OBJECTIVE We sought to investigate the link between psoriasis, and the risk of new-onset migraine, in a nationwide cohort of the Danish population. METHODS Data ...

BACKGROUND The current subclassification of migraine is according to headache frequency and aura status. The variability in migraine symptoms, disease course, and response to treatment suggest the presence of additional heterogeneity or subclasses within migraine. OBJECTIVE The study objective was to subclassify migraine via a data-driven approach, identifying latent factors by jointly exploi...

Objective: To report the clinical events leading to alteration of an anticoagulation regimen for patients undergoing transcatheter closure of an atrial shunt and how this affected migraine symptoms after the closure procedure. Method: Audit of a change of anticoagulant regimen. Results: In the first few weeks after a closure procedure migraine frequency and severity increased despite treatment ...

OBJECTIVES Clinical and genetic characterisation of families in the west of Scotland with familial hemiplegic migraine. METHODS Families with familial hemiplegic migraine were identified via probands attending the regional paediatric neurology and child development centre. All available family members were assessed clinically and genetic linkage studies for the known familial hemiplegic migra...

BACKGROUND/AIMS Many migraine patients develop nausea and/or vomiting (N/V) and are referred to gastroenterologists. This can lead to an inappropriate treatment and a delay of the correct diagnosis. We therefore aimed to identify predictors for migraine in patients presenting with N/V as well as headache. METHODS A total of 407 patients who were first diagnosed with migraine at Samsung Medica...

OBJECTIVE To determine the 3-month prevalence rate of migraine in a health maintenance organization (HMO) population, using a 2-stage screening process and neurologist exam, and to examine the burden of illness associated with both previously diagnosed and previously undiagnosed migraine in this population METHODS A migraine assessment was sent to a random sample of 1,000 HMO patients between...