conclusions in conclusion, the extract of feverfew showed a significant migraine prophylactic effect with no adverse events. results in the case group, after three months of treatment with feverfew, the midas score was reduced to 19.18 ± 4.02. compared to control group, the changes in intensity and frequency of migraine, in the treatment group was significant, at the end of the study (p < 0.05)...

background: migraine is a chronic disease that affects nearly 6% of men and 18% of women worldwide. there are various drugs, which can successfully decrease migraine symptoms and frequency of migraine attacks, but these drugs usually are expensive. hence, this study aimed to assess the effects of pyridoxine  supplementation on severity, frequency and duration of migraine attacks as well as head...

Objective To evaluate cutaneous allodynia among patients with chronic and episodic migraine in a tertiary headache clinic. Methods 80 subjects with episodic migraine and 80 with chronic migraine were assessed in a tertiary hospital. The 12-item Allodynia Symptom Checklist/Brazil questionnaire was applied to classify subjects according to the presence and severity of cutaneous allodynia. Res...

Introduction: Due to the unwanted effects of the migraine headaches of the patient and the role played by excitement and stress in the development and exacerbation of such headaches, migraine headaches are considered among psychosomatic disorders affecting the psychological life of the patients. The present study aimed to investigate the effectiveness of compassion-focused therapy (CFT) for imp...

background: association between helicobacter pylori (hp) infection and migraine and the effect of hp eradication on relief of migraine headache have been studied but the results are controversial. objectives: to evaluate the effect of hp eradication in treatment of patients affected by migraine. materials and methods: eighty consecutive hp infected patients affected by migraine without aura wer...

BACKGROUND Migraine is a common neurological disorder with a significant genetic component. Less information is known about the contribution of minor genetic variations, such as single nucleotide polymorphism (SNP) on the migraine process. In the present study, we aim to investigate the role of CACNA1A gene polymorphism on severity and related factors in family positive migraine patients. MAT...

BACKGROUND To estimate utility values for different levels of migraine pain severity from a United Kingdom (UK) sample of migraineurs. METHODS One hundred and six migraineurs completed the EQ-5D to evaluate their health status for mild, moderate and severe levels of migraine pain severity for a recent migraine attack, and for current health defined as health status within seven days post-migr...